GenomeNet

Database: UniProt
Entry: A0A0Q9Q546_9ACTN
LinkDB: A0A0Q9Q546_9ACTN
Original site: A0A0Q9Q546_9ACTN 
ID   A0A0Q9Q546_9ACTN        Unreviewed;       489 AA.
AC   A0A0Q9Q546;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   05-JUL-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ASG76_12285 {ECO:0000313|EMBL:KRE94163.1};
OS   Nocardioides sp. Soil774.
OC   Bacteria; Actinobacteria; Propionibacteriales; Nocardioidaceae;
OC   Nocardioides.
OX   NCBI_TaxID=1736408 {ECO:0000313|EMBL:KRE94163.1, ECO:0000313|Proteomes:UP000051100};
RN   [1] {ECO:0000313|EMBL:KRE94163.1, ECO:0000313|Proteomes:UP000051100}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Soil774 {ECO:0000313|EMBL:KRE94163.1,
RC   ECO:0000313|Proteomes:UP000051100};
RA   Millard Andrew;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KRE94163.1, ECO:0000313|Proteomes:UP000051100}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Soil774 {ECO:0000313|EMBL:KRE94163.1,
RC   ECO:0000313|Proteomes:UP000051100};
RA   Vorholt J.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRE94163.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; LMSM01000008; KRE94163.1; -; Genomic_DNA.
DR   RefSeq; WP_056603789.1; NZ_LMSM01000008.1.
DR   EnsemblBacteria; KRE94163; KRE94163; ASG76_12285.
DR   Proteomes; UP000051100; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000051100};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051100}.
FT   DOMAIN      180    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     188    195       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   489 AA;  55221 MW;  6E63668F21CAB4D7 CRC64;
     MRSKGGPVDD QQVDLGTAWQ QIVEDLQPNQ RAWLRPSVPV TLHENTAIIA VPNDFTRNQL
     EGRLRNHIED ALTEGFGREI RMLVTVNPAL EDAPTNHVDE SIDRSVSLST NDAQYDAPYD
     PAPVAPAEHL EPTTGSAERR PSALETRLNP KYTFETFVIG SSNRFPHAAA VAVAEAPGKA
     YNPLLVYGES GLGKTHLLHA IGHYVRSLYS NAKVRYVSSE EFTNEFINAI RDDRQDRFKR
     RYRDVDVLLI DDIQFLEGKT QTQEEFFHTF NTLHNANKQI VLTSDRAPKR LEALEDRLRN
     RFEWGLITDV QPPDLETRIA ILRKKAAMDR LTAPPDVLEF IASKIQTNIR ELEGALIRVT
     AFANLNRQEV DMTLAEIVLK DLIPEGGEPE ITHALIIAQT AAYFGVSLED LTGPSRGRHL
     VMARQIGMYL CRELTSMSLP QIGREFGGRD HTTVMYADRK IRQLLAERRA VFNQVSELTN
     RVKMQARQA
//
DBGET integrated database retrieval system