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Database: UniProt
Entry: A0A0Q9WNE2_DROVI
LinkDB: A0A0Q9WNE2_DROVI
Original site: A0A0Q9WNE2_DROVI 
ID   A0A0Q9WNE2_DROVI        Unreviewed;      1869 AA.
AC   A0A0Q9WNE2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-SEP-2017, entry version 13.
DE   SubName: Full=Uncharacterized protein, isoform F {ECO:0000313|EMBL:KRF82366.1};
GN   Name=Dvir\GJ18738 {ECO:0000313|EMBL:KRF82366.1};
GN   ORFNames=Dvir_GJ18738 {ECO:0000313|EMBL:KRF82366.1}, GJ18738
GN   {ECO:0000313|FlyBase:FBgn0205890};
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244 {ECO:0000313|EMBL:KRF82366.1, ECO:0000313|Proteomes:UP000008792};
RN   [1] {ECO:0000313|EMBL:KRF82366.1, ECO:0000313|Proteomes:UP000008792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; CH940651; KRF82366.1; -; Genomic_DNA.
DR   RefSeq; XP_015026391.1; XM_015170905.1.
DR   GeneID; 6631395; -.
DR   FlyBase; FBgn0205890; Dvir\GJ18738.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014873; VDCC_a1su_IQ.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   Pfam; PF08763; Ca_chan_IQ; 1.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00167; CACHANNEL.
DR   SMART; SM01062; Ca_chan_IQ; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008792};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008792};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   TRANSMEM     40     57       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     78     98       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    104    125       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    191       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    257    278       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    290    312       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    442    460       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    472    490       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    567    589       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    643    667       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    768    787       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    807    828       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    837    855       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    904    926       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1018   1043       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1099   1117       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1129   1147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1223   1241       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1312   1337       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1353   1388       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED      670    712       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1869 AA;  214749 MW;  3FF5CD61BC9FC496 CRC64;
     MGGPKKEENP PGGGPTSLFI LTEDNPIRKY TRFIIEWPPF EYAVLLTIIA NCVVLALEEH
     LPEGDKTVLA QKLEKTEAYF LCIFCVEASL KILALGLVLH KHSYLRNIWN IMDFFVVVTG
     FMTQYPQMGP EVDLRTLRAI RVLRPLKLVS GIPSLQVVLK SIIKAMAPLL QIGLLVLFAI
     VIFAIIGLEF YSGALHKTCY SLEDPNKLVK EGESETPCNT DNSTEKAGGS FVCNSTTSMC
     LEKWDGPNSG ITSFDNIGFA MLTVFQCITM EGWTSILYWT NDALGSTFNW IYFVPLIVIG
     SFFMLNLVLG VLSGEFAKER EKVENRQEFL KLRRQQQLER ELNGYVEWIC KAEEVILAEE
     RTTEEEKMHI MEARRRNAAK RKKLKSLGKS KSTDTEEEEA EEDYGDDGYL KTRSKPQGSC
     TGFWRAEKRF RFWIRHTVKT QWFYWFVIVL VFLNTVCVAV EHYGQPTFLT EFLYYAEFIF
     LGLFMSEMFI KMYALGPRIY FESSFNRFDC VVISGSIFEV IWSEVKGGSF GLSVLRALRL
     LRIFKVTKYW SSLRNLVISL LNSMRSIISL LFLLFLFILI FALLGMQLFG GQFNLPGGTP
     ETNFNTFPIA LLTVFQILTG EDWNEVMYQG IISQGGAKKG MIYSIYFIVL VLFGNYTLLN
     VFLAIAVDNL ANAQELTAAE EEQVEEDKEK QLQELEKEME ALQGDGVHLE NGDGTVATSK
     GKSKKKEEEK KEEEEVTEGP KPMLPYSSMF ILSPTNPIRR GAHWVVNLPY FDFFIMVVIS
     MSSIALAAED PVRENSRRNK ILNYFDYAFT GVFTIEMLLK IVDLGVILHP GSYLREFWNI
     MDAVVVICAA VSFGFDMSGS SAGQNLSTIK SLRVLRVLRP LKTIKRVPKL KAVFDCVVNS
     LKNVVNILIV YILFQFIFSV IGVQLFNGKF FYCTDESKHT SEECQGSYFK YEEDELLPKQ
     EMRVWKPRSF HYDNVAAAML TLFAVQTGEG WPQVLQHSMA ATYEDRGPIQ NFRIEMSIFY
     IVYFIVFPFF FVNIFVALII ITFQEQGEAE LQDGEIDKNQ KSCIDFTIGA RPLERYMPKN
     RNTFKYKVWR IVVSTPFEYF IMMLIVFNTL LLMMKYHNQS EMYEKSLKYI NMGFTGMFSV
     ETVLKIIGFG VKNFFKDPWN IFDLITVLGS IVDALWMEFG HDDSNSINVG FLRLFRAARL
     IKLLRQGYTI RILLWTFVQS FKALPYVCLL IAMLFFIYAI IGMQVFGNIK LGTVENSITR
     HNNFQSFIQG VMLLFRCATG EAWPNIMLAC LKGKACDDDA EKGAGEYCGS TLAYAYFVSF
     IFFCSFLMLN LFVAVIMDNF DYLTRDSSIL GAHHLDEFVR IWAEYDPNAT GRIHYTEMYD
     MLKNMDPPLG FGNKCPNRLA YKKLIRMNMP LDDELRVQFT TTLFALIREN LSIKMRAPEE
     MDQADIELRE TITNIWPLQA KKMLNLLVPP IDQLNKGKLS VGKIYAGFLI LESWRNTRFG
     QIDSGMPNWK ERKKPDDDDD RKCSPTAVEE PMLDLQDSSR HPSQESLTGP DAGHLHPGHS
     YINGHRHSPS LRHNGSPLAR SPSPRRRGHQ YIHHDIGFSD TVSNVVEMVK ETRHPRHSNS
     HQRYPRGSWS ASTSPARSPS PSRYGGHLSR SKRTQLPYPT YGTTSLCQRS RSPSPARLQE
     MRERDRLGYG IDMGGPHVQH SYPTLASRRA GIGRRLPPTP SKPSTLQLKP TNINFPKLNA
     SPTHTHHSTP HSVHSLPHHR DLLRDPREVY YSSRERDRDR DRFRDRDRLH EYDLRYEYRD
     RERELYERER EREREVERER LEYIAPLSFE QALAMGRTGR VLPSPVLNGF KPKSGLNTRH
     SDSDEEDWC
//
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