ID A0A0R1GEA4_9LACO Unreviewed; 602 AA.
AC A0A0R1GEA4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Signal transduction diguanylate cyclase {ECO:0000313|EMBL:KRK32574.1};
GN ORFNames=FC07_GL002000 {ECO:0000313|EMBL:KRK32574.1};
OS Loigolactobacillus bifermentans DSM 20003.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Loigolactobacillus.
OX NCBI_TaxID=1423726 {ECO:0000313|EMBL:KRK32574.1, ECO:0000313|Proteomes:UP000051461};
RN [1] {ECO:0000313|EMBL:KRK32574.1, ECO:0000313|Proteomes:UP000051461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20003 {ECO:0000313|EMBL:KRK32574.1,
RC ECO:0000313|Proteomes:UP000051461};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK32574.1}.
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DR EMBL; AZDA01000140; KRK32574.1; -; Genomic_DNA.
DR RefSeq; WP_057905838.1; NZ_AZDA01000140.1.
DR AlphaFoldDB; A0A0R1GEA4; -.
DR STRING; 1423726.FC07_GL002000; -.
DR PATRIC; fig|1423726.3.peg.2076; -.
DR OrthoDB; 2249567at2; -.
DR Proteomes; UP000051461; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051461};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 238..374
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 371..602
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 602 AA; 68350 MW; 1C8102039E00624A CRC64;
MDQVNLPLGL WLVQTLAATF LITGFVSFER YLWRQATLVT QQLRATYRVL QWLLPLGVAL
LFEYGTYQGF MESNMLANIG VAMIVLPLFD EAVTNWGYAW RGLGVVVIWG LQRGSTLTRN
WPLLVLLLVN LLLIRRTHHM LRHTPHWIFV ITVSMVFSFW LDVTWAPFTA QLAWQAAGMY
LVICTFVALF WARTHRKFLL DQQMQALIDY DDVVNDTTVA QDRAVAASLF RGAQVHHEPL
TVAAFDVDHF KQFNQAYGHM AGNATLMAVT QTLRQVLDQT QVAYQLNHLG GEEFSLLLPK
VGLAQAITVV NQCLTQVRTT AFPVEHTTAQ VTLSAGVTTL HEQDQSVDSL YKRADDSLYI
SKIHGHDVLT VEGQTTTYDR DVDVNQLAYF AQPIEGVNAQ GSVHWAAELL LRRYDSQSDQ
WRLPARFDIA VDKQIVLISQ ALTVLNVQRV NVNLTLAQFS DIETAKSLVS YMHSGRGPQQ
LTIEITDVPS VTVMRRVSAL YREAGILIYI DDVGSDNSYE LVQKLLPYVN GVKFAIQNLR
RQESSARIHE RIQFWLDIAQ RQEISFILEG LEFPDEVTWA QHLGIQYFQG YYFGKPQLPL
TA
//
