ID A0A0R1GR53_9LACO Unreviewed; 794 AA.
AC A0A0R1GR53;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN ORFNames=FD07_GL000655 {ECO:0000313|EMBL:KRK36525.1};
OS Levilactobacillus parabrevis ATCC 53295.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Levilactobacillus.
OX NCBI_TaxID=1267003 {ECO:0000313|EMBL:KRK36525.1, ECO:0000313|Proteomes:UP000051176};
RN [1] {ECO:0000313|EMBL:KRK36525.1, ECO:0000313|Proteomes:UP000051176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53295 {ECO:0000313|EMBL:KRK36525.1,
RC ECO:0000313|Proteomes:UP000051176};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964,
CC ECO:0000256|HAMAP-Rule:MF_01403};
CC -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC ECO:0000256|HAMAP-Rule:MF_01403}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK36525.1}.
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DR EMBL; AZCZ01000019; KRK36525.1; -; Genomic_DNA.
DR RefSeq; WP_020089494.1; NZ_KB911383.1.
DR AlphaFoldDB; A0A0R1GR53; -.
DR STRING; 357278.IV61_GL000698; -.
DR PATRIC; fig|1267003.4.peg.696; -.
DR eggNOG; COG3957; Bacteria.
DR OrthoDB; 9768449at2; -.
DR Proteomes; UP000051176; Unassembled WGS sequence.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02011; TPP_PK; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR HAMAP; MF_01403; Phosphoketolase; 1.
DR InterPro; IPR023962; Phosphoketolase.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR PANTHER; PTHR31273:SF1; PHOSPHOKETOLASE-RELATED; 1.
DR Pfam; PF03894; XFP; 1.
DR Pfam; PF09363; XFP_C; 1.
DR Pfam; PF09364; XFP_N; 1.
DR PIRSF; PIRSF017245; Phosphoketolase; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW Thiamine pyrophosphate {ECO:0000256|HAMAP-Rule:MF_01403}.
FT DOMAIN 9..373
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09364"
FT DOMAIN 590..790
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09363"
SQ SEQUENCE 794 AA; 89860 MW; 7C0DBD07446FECBB CRC64;
MANADFDSKA YLEGVDKYWR AANYLSVGQL FLRDNPLLKR DLTSDDVKIK PIGHWGTIVS
QNFIYAHLNR AILKYDLNMF YIEGSGHGGQ VMVSNSYLDG SYSEIYPNIS QDEEGLKRLF
KQFSFPGGVA SHAAPETPGS IHEGGELGYS LSHGTGAILD NPDVIAAVEI GDGESETGPL
AASWFSDKFI NPIKDGAVLP IINMNGFKIS NPTILSRMSD EDLTKYFEGM GWDPHFVEIE
AGDTDFMRVH EDMAKTMDEV IGKIKAIQKN ARENNDETLP KWPMIIFRSP KGWTGPKADL
DGNPIEGSFR AHQVPIPVAA GDMEHADMLV NWLKSYKPEE LFNEDGSVKQ EVRDMAPKGE
QRMAMNPITN GGIKPQPLKL PDYKKYAVDT TEHGKTIAQD MLVWSDYLAD VMKLNPETFR
GFGPDETKSN RLYAALDYGK RQWMEGIKEP NDENMAHEGR IIDSQLSEHQ AEGWLEGYVL
TGRHGYFATY ESFGRVVDSM LTQHFKWLRK AAEQEWRHDY PSLNFVDTST VFQQDHNGYT
HQDPGMLTHL AEKKPAFIRE YLPADANTLL AVGDVAFRSR EKINLIVTSK HPRPQWFSID
EATNLVHNGL GYIDWASTDQ GQEPDVVFAA AGTEPTWESL AAISLLHDEF PEMKIRFINV
VDLLKLRSPK LDPRGISDDE FDRLFTTDKP VIFAFHGFEG LVKDLFFDRH NHNLHVHGYR
ENGDITTPFD MRVLNHLDRY HLAKEAVDDI DAYAVKGAYF AQRMDDMVAK HNAYIREVGT
DLPEVNAWQW KPLK
//
