ID   A0A0R1GRV0_9LACO        Unreviewed;       245 AA.
AC   A0A0R1GRV0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Crp-like transcriptional regulator {ECO:0000313|EMBL:KRK36860.1};
GN   ORFNames=FD07_GL000446 {ECO:0000313|EMBL:KRK36860.1};
OS   Levilactobacillus parabrevis ATCC 53295.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Levilactobacillus.
OX   NCBI_TaxID=1267003 {ECO:0000313|EMBL:KRK36860.1, ECO:0000313|Proteomes:UP000051176};
RN   [1] {ECO:0000313|EMBL:KRK36860.1, ECO:0000313|Proteomes:UP000051176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53295 {ECO:0000313|EMBL:KRK36860.1,
RC   ECO:0000313|Proteomes:UP000051176};
RX   PubMed=26415554; DOI=10.1038/ncomms9322;
RA   Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA   Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA   Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA   Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA   de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA   Zhang H., O'Toole P.W.;
RT   "Expanding the biotechnology potential of lactobacilli through comparative
RT   genomics of 213 strains and associated genera.";
RL   Nat. Commun. 6:8322-8322(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRK36860.1}.
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DR   EMBL; AZCZ01000015; KRK36860.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R1GRV0; -.
DR   STRING; 357278.IV61_GL000493; -.
DR   PATRIC; fig|1267003.4.peg.481; -.
DR   eggNOG; COG0664; Bacteria.
DR   Proteomes; UP000051176; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR24567:SF79; CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR CRP; 1.
DR   PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   PRINTS; PR00034; HTHCRP.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
FT   DOMAIN          35..155
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          169..237
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51063"
SQ   SEQUENCE   245 AA;  26677 MW;  5F9BAEED7C671D64 CRC64;
     MAGKQDFKGD VVMESVHTHE HSIERELECV SQVPIFQRLS AEQMTSVAQV TRPIHAEKGG
     AVFSTGEVSQ TLYIVNQGQV RLYHLAEDGR EQVLRVLNPG DFVGEIALFT DEIHASYAEA
     TKTTELCTIS RASLTALIKK LPPLSMALLG ALADRLKSAE RQATLLAIPD ALPRLAGYLQ
     ELTGHTTGTV DLPMSKQDLA AYLGMTPESL SRKLRQLATS GIIETIGRRQ VKVTDSIKLS
     ELAPS
//