ID A0A0R1JW10_9LACO Unreviewed; 430 AA.
AC A0A0R1JW10;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=DNA-directed DNA polymerase {ECO:0000313|EMBL:KRK72889.1};
GN ORFNames=FD02_GL001307 {ECO:0000313|EMBL:KRK72889.1};
OS Lacticaseibacillus nasuensis JCM 17158.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1291734 {ECO:0000313|EMBL:KRK72889.1, ECO:0000313|Proteomes:UP000051804};
RN [1] {ECO:0000313|EMBL:KRK72889.1, ECO:0000313|Proteomes:UP000051804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 17158 {ECO:0000313|EMBL:KRK72889.1,
RC ECO:0000313|Proteomes:UP000051804};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK72889.1}.
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DR EMBL; AZDJ01000016; KRK72889.1; -; Genomic_DNA.
DR RefSeq; WP_056950826.1; NZ_AZDJ01000016.1.
DR AlphaFoldDB; A0A0R1JW10; -.
DR STRING; 1291734.FD02_GL001307; -.
DR PATRIC; fig|1291734.4.peg.1344; -.
DR OrthoDB; 9808813at2; -.
DR Proteomes; UP000051804; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:KRK72889.1};
KW Mutator protein {ECO:0000256|ARBA:ARBA00022457};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:KRK72889.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051804};
KW Transferase {ECO:0000256|ARBA:ARBA00022932, ECO:0000313|EMBL:KRK72889.1}.
FT DOMAIN 16..205
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 430 AA; 48339 MW; 8266A6D057A37260 CRC64;
MSTPLDDPRR LPSHDIMCID CKSFYASVEA IRRSEYPLAA KNAVLSRAES AGGLVLAGSP
LAKANYGVRL GTRKFELRPD MDVQVVPPHM ADYIKINYQI NEIYRQFTDD LHWYVYSIDE
SFIDVTHSHS LFGSNAEIAS RIQDKVFQAT GIITTVGIGQ NPLLAKLALD NEAKKQAPWQ
ATWTYDRVPE TIWKINELTD FWSIGSRTAI KLHNMGIYTL YDVAHTPLAR LKKKFGVLGE
AMYYHAWGID YSLLERRYVP REDNKGYGNS QVLMRDYTTL EDCETVLSEI ADQVATRLRK
HEVQGEVVGI SVGFAEPDAS GQTHWGAQVH IDPTNRTDDL IRAVKYLFES KWQGDALRNV
GVRVNKISHP SSFQLSLFEP SQREQANGRL EHAIDQIRSR YGYKAIVRGS SKTAGGTAID
RAGMIGGHQA
//
