ID A0A0R1QIH7_9LACO Unreviewed; 1010 AA.
AC A0A0R1QIH7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KRL44393.1};
GN ORFNames=FD29_GL000046 {ECO:0000313|EMBL:KRL44393.1};
OS Companilactobacillus mindensis DSM 14500.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Companilactobacillus.
OX NCBI_TaxID=1423770 {ECO:0000313|EMBL:KRL44393.1, ECO:0000313|Proteomes:UP000050872};
RN [1] {ECO:0000313|EMBL:KRL44393.1, ECO:0000313|Proteomes:UP000050872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14500 {ECO:0000313|EMBL:KRL44393.1,
RC ECO:0000313|Proteomes:UP000050872};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL44393.1}.
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DR EMBL; AZEZ01000043; KRL44393.1; -; Genomic_DNA.
DR RefSeq; WP_057887797.1; NZ_AZEZ01000043.1.
DR AlphaFoldDB; A0A0R1QIH7; -.
DR STRING; 1423770.FD29_GL000046; -.
DR PATRIC; fig|1423770.3.peg.44; -.
DR Proteomes; UP000050872; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 819..838
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 845..866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 881..902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 914..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 951..978
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 850..975
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 987..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 107667 MW; 66E566A27CFDD68C CRC64;
MRKNKYWMAL VGWIVVVVVA ILAMPNVSQL VRNKGNITLP NYTESQKAAN LQKKANGNKS
VTTYTVVFDN KGAGKLSANQ SKEIDNKLNE LSNKKLLKVT SVMGPSDNAE TKKQLIAKDK
STQLAQVTVK KNNYVGQQVQ SLQDQLKISG IKTYVTGADA LNDEFSTVTE KGIQKTEVIA
IIFIFIVLIL VFRSPIVPLI SLLNVGVAFV TSLSIVMNLA EKINFPISNF TQVFLVVVLF
GIGTDYNILL YNYFKGALAR GLSANEAAHD AQKHGGRTIL YSGISVLIGF SVLALAKFSF
YRSAVGVAIG VLVLLSVLLT LNMFFMQTLG EKMFWPSKVT AGRGKSRIWY GLSRAALTYP
VVILGIIAIA AVPFLINTSS TLNFNNADEV PDTYQAKKGY EVIQDHFSKG MSAPATVYIE
GNSKMTTQAK LAAIDDLTNY LQKEPGVKTV TSATQPGGNK IKSMYLKNQL VSITNGLNTS
TAGLEKIKSG LNSASSQLQS ANISGSTAQV QALADGTNEL QAGAQQLSSG ITEYTNGVSS
VNSGLQSANS QLPTLTSGVS TLTSSSAQLS SGMSQLQSQV NSISSQATQL MALLQSSGQD
TTAAQTQVAA LQSSISQLSS GSAAISSGMS QLNGQMPTLT SGMSTLASGT NTLAASSSTL
TSGGQSVASG ATTVNSGVQQ MNTQLKQMSS QVTQLESGLT SANDGLDTIA RGNTTMKTYL
DGLRKSYVGD TFYLPKDTIK SSAFKPALDA YMNKDRKIAE LTIVFKGDPN SETTSKQLKT
IQSDMKAQLK HGALKDAKVA VGGQTSQNND LRTLANGDFG RTALIMTVGI GIALIVVTES
ILQPLTIIGT LLLAYEVSLG ITRIFSKMVL GINLLSWNTP FFTFIMLMAL GVDYSIFLMI
RFKDEPMPDL KDRMLNAATA IGPVVISAAI ILSGTFAALM PSGVTTLIQV ALGVIFGLII
LVIILPMTLS ALISLTMWHE KRMFQVKKPA KKAKDTTEDS DSASDPKTEN
//
