ID A0A0R1VYI1_9LACO Unreviewed; 792 AA.
AC A0A0R1VYI1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:KRM10399.1};
GN ORFNames=FC15_GL001373 {ECO:0000313|EMBL:KRM10399.1};
OS Lapidilactobacillus concavus DSM 17758.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lapidilactobacillus.
OX NCBI_TaxID=1423735 {ECO:0000313|EMBL:KRM10399.1, ECO:0000313|Proteomes:UP000051315};
RN [1] {ECO:0000313|EMBL:KRM10399.1, ECO:0000313|Proteomes:UP000051315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17758 {ECO:0000313|EMBL:KRM10399.1,
RC ECO:0000313|Proteomes:UP000051315};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM10399.1}.
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DR EMBL; AZFX01000038; KRM10399.1; -; Genomic_DNA.
DR RefSeq; WP_057824186.1; NZ_AZFX01000038.1.
DR AlphaFoldDB; A0A0R1VYI1; -.
DR STRING; 1423735.FC15_GL001373; -.
DR PATRIC; fig|1423735.3.peg.1420; -.
DR OrthoDB; 9765586at2; -.
DR Proteomes; UP000051315; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.275.40; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR042493; XPD_DNA_FeS.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KRM10399.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051315}.
FT DOMAIN 183..427
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 792 AA; 90563 MW; 1BA352B7A0D738AC CRC64;
MTKPQRLGIR ELIEFTLKSG DLISDASSNH TALEGARIHR RLQKKAGPDY QKEIYLCYET
KLDDQDFKIE GRADGVIIDP DTHEILVDEI KTSEPDFADL TKDALTRYWG QAKFYAWLLA
ERESVDQVTV QLTYFQTTTE LVTQKQEVHT HEDLTTFAQG VLKEYEYWLH LRSQWQLQRN
AAAKKLAFPY SDFRAGQRQF SAIVYKTIAA QKILLTEAPT GTGKTIATLF PAIKAFAEQD
VQRIFYLTAK TSTRTVAESA LTDLANEGAR LKRVTITAKD KIAFPVPEGY PAGHSPYTDG
YYDRNKDALK DLFAHEDQWD RTTIETYAKK WTIDPFEFSL DASLFADVII GDYNYLFDPQ
VYLQRFFANP KPGNVFLIDE AHNLVSRSRA MYSADLVETP MKQIERDIRG QKSQVVADLH
KALKPIENSF KILPDMLPEP VQETSVIDEP DEDFIAGFYL GLEALGTWMA KNEEHPVYEK
VRDYFFTLNS FLKIYELYGD NYRTIIRLAP TASLTLQCLD PSQFLQDCLH KGDAAVLFSA
TLTPLDYYRE TLTAADENAL VYRMTSPFPP QNQCLIITNY IQTTYAQRTA NLPRILQALQ
SLVDAKKGNY LVFLPSYSYL TEIVDAFIQK NPTLQIIRQE SSDTEATRQD FLDHFQTNPQ
ETLVGFAVLG GAFAEGIDLR RDRLIGVAII SVGLPGLSLE HDLLRDYYQL KNHQGFAYAY
QLPGFNNVMQ AGGRVIRGNE DRGVILLIDQ RFASARYQRL FPPHWQQQHQ VKNVDQLKEA
LLGFWERPKE KS
//
