ID A0A0R1XPV0_9LACO Unreviewed; 315 AA.
AC A0A0R1XPV0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RNA-directed DNA polymerase {ECO:0000313|EMBL:KRM28998.1};
GN ORFNames=FC91_GL001162 {ECO:0000313|EMBL:KRM28998.1};
OS Schleiferilactobacillus harbinensis DSM 16991.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1122147 {ECO:0000313|EMBL:KRM28998.1, ECO:0000313|Proteomes:UP000050949};
RN [1] {ECO:0000313|EMBL:KRM28998.1, ECO:0000313|Proteomes:UP000050949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16991 {ECO:0000313|EMBL:KRM28998.1,
RC ECO:0000313|Proteomes:UP000050949};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the bacterial reverse transcriptase family.
CC {ECO:0000256|ARBA:ARBA00034120}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM28998.1}.
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DR EMBL; AZFW01000020; KRM28998.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1XPV0; -.
DR PATRIC; fig|1122147.4.peg.1201; -.
DR OrthoDB; 9788687at2; -.
DR Proteomes; UP000050949; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd03487; RT_Bac_retron_II; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000123; Reverse_transcriptase_msDNA.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF00078; RVT_1; 1.
DR PRINTS; PR00866; RNADNAPOLMS.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Nucleotidyltransferase {ECO:0000313|EMBL:KRM28998.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050949};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:KRM28998.1};
KW Transferase {ECO:0000313|EMBL:KRM28998.1}.
FT DOMAIN 33..245
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 315 AA; 36019 MW; A8A9CF19CB103890 CRC64;
MTTKVTKRYL LNQSALYHCT SKRKLARVLQ IDLKRLVGIV GDIPNQYSTI TRPKKDSGER
IVHNAHFELK RVQRRLFTLL RRVKRPNWLI SGEIGKSITD NVRPHLGGTQ LLKIDISGFF
DNCSRESVYQ FFHVQMAQPS DVAKICTDLC TLENAVVQGA STSMLIAFYA NQSMLQELHE
LAEDNSLIFT VYVDDIAFSS SHSFQASDIL DQATRIVSAY GFRVKNKKVR AYNDSRPKLL
TGVIITTTSK MAVPNCKRRK ILDDMTQYRR STNPAERRSM RSKILGQISA AQQIEPDFFT
GVKNQLKYEM RMDED
//
