ID A0A0R1ZB44_9LACO Unreviewed; 373 AA.
AC A0A0R1ZB44;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Site-specific DNA-methyltransferase {ECO:0000313|EMBL:KRM51905.1};
GN ORFNames=FC64_GL001098 {ECO:0000313|EMBL:KRM51905.1};
OS Ligilactobacillus araffinosus DSM 20653.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423820 {ECO:0000313|EMBL:KRM51905.1, ECO:0000313|Proteomes:UP000051291};
RN [1] {ECO:0000313|EMBL:KRM51905.1, ECO:0000313|Proteomes:UP000051291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20653 {ECO:0000313|EMBL:KRM51905.1,
RC ECO:0000313|Proteomes:UP000051291};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM51905.1}.
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DR EMBL; AYYZ01000029; KRM51905.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1ZB44; -.
DR STRING; 1423820.FC64_GL001098; -.
DR PATRIC; fig|1423820.4.peg.1123; -.
DR Proteomes; UP000051291; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KRM51905.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051291};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:KRM51905.1}.
FT DOMAIN 41..152
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 373 AA; 42436 MW; B6092EE66936F55F CRC64;
MEIIATCAAG IEGILGNELK HLGYHANVEN GRVRLEGDFQ DIIRLNLWLR TADRVKIVLA
KFMAKTFDDL FENVKQIPWE DWLALDAAFP VSGKSQKSQL HNVPSVQAIT KKAIVERMNQ
TYHRRTKFPE TGAEYPVQVS INKNKAMITL DTTGSSLFKR GYRLDKGGAP MKENMAAALV
LLSHWYPEDP FMDPVCGSGT IPIEAALLGR NIAPGINRHF VCEQWQQVDE TMVSKLREEA
RAAQKPKVEL DIVGYDIDGR MINISKVNAK AAGVLHNIHF KQLAVKDFNT DKENGVIVAN
PPYGQRLSDR DSVHVLYEQM GKIYRPMTTW SKYILTSDLN FEKYYGEQAT KRRKLYNGSL
RTDLFQYWGK KKR
//
