ID   A0A0R2AZS2_9LACO        Unreviewed;       709 AA.
AC   A0A0R2AZS2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Membrane associated transglutaminase family enzyme {ECO:0000313|EMBL:KRM72608.1};
GN   ORFNames=FC34_GL000317 {ECO:0000313|EMBL:KRM72608.1};
OS   Lacticaseibacillus brantae DSM 23927.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=1423727 {ECO:0000313|EMBL:KRM72608.1, ECO:0000313|Proteomes:UP000051672};
RN   [1] {ECO:0000313|EMBL:KRM72608.1, ECO:0000313|Proteomes:UP000051672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23927 {ECO:0000313|EMBL:KRM72608.1,
RC   ECO:0000313|Proteomes:UP000051672};
RX   PubMed=26415554; DOI=10.1038/ncomms9322;
RA   Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA   Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA   Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA   Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA   de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA   Zhang H., O'Toole P.W.;
RT   "Expanding the biotechnology potential of lactobacilli through comparative
RT   genomics of 213 strains and associated genera.";
RL   Nat. Commun. 6:8322-8322(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRM72608.1}.
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DR   EMBL; AYZQ01000001; KRM72608.1; -; Genomic_DNA.
DR   RefSeq; WP_057893632.1; NZ_AYZQ01000001.1.
DR   AlphaFoldDB; A0A0R2AZS2; -.
DR   STRING; 1423727.FC34_GL000317; -.
DR   PATRIC; fig|1423727.3.peg.320; -.
DR   Proteomes; UP000051672; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR021878; TgpA_N.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF11992; TgpA_N; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051672};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        586..605
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          454..528
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          532..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..575
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   709 AA;  79038 MW;  3953286349F28A4A CRC64;
     MKTIGLMLYR WILLGWLLFS AGEPFVRINH FSQVPLLIGF SLAMMAISSL VAWRPRLWWV
     ATTLYLSSFL VILWWLFPGR QWLFNFWGRF QEALTNFLTV GGLTMPLIVS VPLVLLVIIF
     LSLLVVGLRH YFIPWLVILS YLLAVHIFNQ EGLINAFAQL ATIGLLLLGL HVFSAQPRRL
     VSMAVITSAM VGLVWGINVN QPQINTTLVD DSVGLRNWLN DRGFYQALND YAHQNMKTGL
     SADSRNLGGP VYDDNTPVVT VEQKTPHYLR ARVLTAYNGK GWNGTANFGS VVPASEVISD
     AQTAYGSPER ITITEPSDAP FAVLPYGQVQ LTQTTPMPVN RLYYNPNQAQ LMASPNRVPT
     RVTLTSRPKT VTATQLNRVS APDLSTDNLR RDTRLPAIPT RVKRLAQQVT ADASTYYAKV
     KAIETYLRTS PNLIYSKVDA RTTPKGRDYV DYFLFDSQVG YCDNFSSAMV VMLRSIGIPA
     RWAMGYNTGT LTTSGKTTDT YTITNANAHS WPEVYFTGFG WLPFEPTPGF ANPASPVTPD
     APVQSSSTSS TSSTSQSVTS SSSAPASSSS STRTAAQTSN RQGLSVWWLL IPGGIIVGLG
     WWLAWRWASV LATLASMGVN SKNFEGRYRG VRWLLQTRWP KVQTMGWHDY AQFIQAQLPE
     SHWDKVTAIY EARRFGGDRQ TVADLRSVAA AFRRYQSEHA GFNRHNQPK
//