ID A0A0R2EYP8_9LACO Unreviewed; 1088 AA.
AC A0A0R2EYP8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Gram-positive cocci surface proteins LPxTG domain-containing protein {ECO:0000259|Pfam:PF00746};
GN ORFNames=FC75_GL000859 {ECO:0000313|EMBL:KRN18167.1};
OS Lacticaseibacillus camelliae DSM 22697 = JCM 13995.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1423730 {ECO:0000313|EMBL:KRN18167.1, ECO:0000313|Proteomes:UP000050865};
RN [1] {ECO:0000313|EMBL:KRN18167.1, ECO:0000313|Proteomes:UP000050865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22697 {ECO:0000313|EMBL:KRN18167.1,
RC ECO:0000313|Proteomes:UP000050865};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN18167.1}.
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DR EMBL; AYZJ01000098; KRN18167.1; -; Genomic_DNA.
DR RefSeq; WP_056989991.1; NZ_AYZJ01000098.1.
DR AlphaFoldDB; A0A0R2EYP8; -.
DR STRING; 1423730.FC75_GL000859; -.
DR PATRIC; fig|1423730.4.peg.906; -.
DR Proteomes; UP000050865; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR008929; Chondroitin_lyas.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR SUPFAM; SSF49313; Cadherin-like; 1.
DR SUPFAM; SSF48230; Chondroitin AC/alginate lyase; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000050865};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT TRANSMEM 1062..1081
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1046..1082
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|Pfam:PF00746"
FT REGION 955..1056
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 965..1024
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1088 AA; 118309 MW; 7988362E909A20AC CRC64;
MKHRLAWFGF IMSIAAVFTT ALLPNQETNA AADPAISDAV TLNITKTNGF LHPAISVDPE
QLQNTRRELA TGAQPWQAYY EGMVQSPYAS RDFKAANLKS GTFDTPKDAT FASSGQELTL
SADGFRAYTQ AIMYYLTGQK QYRYNAIRLV RTWENMDPAG FKYYADAHIH APVPFYYMVS
AAELLKFTSV DGNLYTDAEG NQVNLNWTST DNSKLTQNLI DPLVTNLLIK TKDQYFAQHL
YPLTGALAAA IFKNDQAAYT DAVEQTFVNA GSSRPNINGA LNNLFHQMSA DDPRNPVKQD
FVEHLEMGRD ANHAKDDVFC FTGLARVINN QGTLVDPTTG EPSTAANAVD PYQFGNNRLI
EGAEQFYRYN DGETIPWIQV SKPGDTTHPA IEADGVQNII DFGGAVSTDG RGRMNKPYTS
SELYDYYRFQ EGLSAAEIAK RYPAVATQAT HLNGTTFYEG TTALNYWGVY SDNKITEIGT
DYWLSMPAAK GSDSATFPSA PATNADVSFI QHGTILDENH AQLTKDGITV EAVSDQKDIK
ETAYDKRYPQ DTTTARGGSQ IALAGLVKPT DGYFAIKLKT NGVAKLLISS SNLPNKAYQT
LTLPNTKNQW QTVAYPTNGG QAYMDFYAVV GKSSTKVTFA AASYTDQAAL PVIGETARDT
AVFLGHTITL KLSATNATTL TLADGPKGLQ LAADGTLSWK PTAAGDYPVT VTATNGQRTV
NKTFTISVKK DRTTAYNQAT QQLSEGVYTT ASMAKINTAA KAVINLLDHG DDAAFQSALT
AYTEAIKQGE LLNPTLEDHS LNYAAYPDMT IANLLTKDTL SLDPKQTFNT TALVDNDPAS
YGGDWMTPAV LDFGENYRVT LTSSSFLART GFPNRTQGAN LYGSNDAKTW TKLTTTTTKR
DNQMQTVAID QAQQGIAYRY IKIQVDEPGE PTDPAWPGIA SFADIHLFGT RTEVTKDAAG
STRPKLLSEP SQPALDDHST NQTEVTNPTK KPSQPTGSDA SFNHGQSTAA SRGHNHPSAD
QSSIKAEAKS KKPAPIKANR TSVKQDKHAR KAYPQTGESH RLTYSIAGLL IAAVSALLMI
ARVKRANR
//
