ID A0A0R2H2P1_9LACO Unreviewed; 1032 AA.
AC A0A0R2H2P1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Nuclease SbcCD subunit C {ECO:0000256|ARBA:ARBA00013368};
GN ORFNames=IV41_GL000562 {ECO:0000313|EMBL:KRN44247.1};
OS Limosilactobacillus ingluviei.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=148604 {ECO:0000313|EMBL:KRN44247.1, ECO:0000313|Proteomes:UP000051639};
RN [1] {ECO:0000313|EMBL:KRN44247.1, ECO:0000313|Proteomes:UP000051639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14792 {ECO:0000313|EMBL:KRN44247.1,
RC ECO:0000313|Proteomes:UP000051639};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBUNIT: Heterodimer of SbcC and SbcD. {ECO:0000256|ARBA:ARBA00011322}.
CC -!- SIMILARITY: Belongs to the SMC family. SbcC subfamily.
CC {ECO:0000256|ARBA:ARBA00006930}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN44247.1}.
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DR EMBL; JQBA01000018; KRN44247.1; -; Genomic_DNA.
DR RefSeq; WP_056994385.1; NZ_JQBA01000018.1.
DR AlphaFoldDB; A0A0R2H2P1; -.
DR STRING; 1203076.GCA_000312405_01307; -.
DR PATRIC; fig|148604.4.peg.570; -.
DR eggNOG; COG0419; Bacteria.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000051639; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRN44247.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRN44247.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:KRN44247.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051639}.
FT DOMAIN 5..213
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 187..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 242..269
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 326..353
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 381..480
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 598..693
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1032 AA; 112098 MW; 90F2E0F70EE793BA CRC64;
MRPLKLELTN FGPYPHSVID FRQFDEAPLF LVTGPTGSGK TTIFDAMVYA LFNETTNNQD
RNAAALRADF APADAATAVN FTFEHAGVVY TLTRTPKQKL KNKQGRVVER AAKVSLTYER
AGESQTLTRI STVDKFIVDL LHLTKEQFKQ LVLLPQGQFR QVLASSSTEK EALLEELFAT
GLYQQWAQAL KEQLANQEAA LKTQNQKLAL LKQAVPQIDA TLPTPTWQAQ AQRQVTAQTT
ALADISREIV AAQAAVQTAN AQLQQAQSVQ ADQAALAKLT AAATQLTAQA PHIQHRQRQL
HALQWYQRQQ TTYLKWQTAQ QDLAAARAAR QTAQTARAEA VQAQQTAEQA AQTLAAQAPT
IEQQQAQRLT LTSQLPEFEA QARLQAQVAT QQRQVEQLTA QVAELTTQRD QQQAQQAQLT
AAVARADAIN AQAVAVERQT NELQQTTAAL TRVQEQQTTL TAAEAKLQTA RQTAQQTAAA
LATAQATLKT QKDTYARAAI RRLAADLQPG SPCPVCGSRD HPHPAPAVAS GEEVTAEMVE
AAETAVTAAI QAASRAASQV SQQEQQVETG RDQFNQQLTA LAQQLGVAAE LPTVAAAVAK
AQDTLTQTRA TLEQEQAAVA QAKQDLQALS APLEQTTTDL ATQTDHLRAA RETLAAQQAQ
LQAQTARLGE RTLAEVKAEI EQLTTRLQTY HQAVTQNQAA LTQAKQDQAV AQSQLTTADK
QATAAQAVSE QTQATLQTAL AAFDPQLTWD FWAQAQADLS QQATWQAKVD AYRQQQAANA
AQQKQLQARL AQAKGTVTVA TAKAALKTAE ATLADRQAAK GQQTEQLAQL QATLKQVATV
VKTQAAHLEE QTELNTLVQV VTGNSTTKLS LPRYVLQTYF SQVLTVANQY LLKLSEQRYS
FKLDEQVGKG RGQKWSGLEI NVHDNQVGQD RSARTLSGGE SFLASLSLAL GLCEEIQRQA
GGVQIDALFI DEGFGSLDQN ALQTALNALL EIQGHRMIGV ISHVTEMKEQ IPDQLVVHSH
DGRSTVSYRH AD
//
