ID A0A0R2H5X8_9LACO Unreviewed; 797 AA.
AC A0A0R2H5X8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Phosphoketolase {ECO:0000313|EMBL:KRN44996.1};
GN ORFNames=IV41_GL001864 {ECO:0000313|EMBL:KRN44996.1};
OS Limosilactobacillus ingluviei.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=148604 {ECO:0000313|EMBL:KRN44996.1, ECO:0000313|Proteomes:UP000051639};
RN [1] {ECO:0000313|EMBL:KRN44996.1, ECO:0000313|Proteomes:UP000051639}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14792 {ECO:0000313|EMBL:KRN44996.1,
RC ECO:0000313|Proteomes:UP000051639};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN44996.1}.
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DR EMBL; JQBA01000007; KRN44996.1; -; Genomic_DNA.
DR RefSeq; WP_019206611.1; NZ_JQBA01000007.1.
DR AlphaFoldDB; A0A0R2H5X8; -.
DR STRING; 1203076.GCA_000312405_01573; -.
DR GeneID; 82934340; -.
DR PATRIC; fig|148604.4.peg.1922; -.
DR eggNOG; COG3957; Bacteria.
DR OrthoDB; 9768449at2; -.
DR Proteomes; UP000051639; Unassembled WGS sequence.
DR GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR Pfam; PF03894; XFP; 1.
DR Pfam; PF09363; XFP_C; 1.
DR Pfam; PF09364; XFP_N; 1.
DR PIRSF; PIRSF017245; Phosphoketolase; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000051639}.
FT DOMAIN 7..377
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09364"
FT DOMAIN 593..793
FT /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT phosphoketolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09363"
SQ SEQUENCE 797 AA; 90220 MW; 437AE43BE4230BF5 CRC64;
MAVDYDSKAY LENVDAYWRA ANYLSVGTLF LMNNPLLRRD LKAEDVKPKP IGHWGTIVPQ
NFIYAHLNRV IKKYGVKMFY IEGSGHGGQV MVNNSYLDGS YTEIYPEITQ DEAGMAKLFK
HFSFPGGTAS HAAPETPGSL HEGGELGYAL SHGVGAILDN PDQIAAVEIG DGEFETGPLA
ASWFSNRFIN PVTDGAVLPI LQVNGFKISN PTMIARMSDE EVTKYFEGLG WKPYFVSAYK
GGDFDALKDH MEVHAEMAKV MDEAIEEIQA IQKKAREDND GSMAQWPVII FRVPKGWTGP
TKDLDGNPIE NSFRAHQIPI PVAQDAMEHK DMLVDWMKSY KPEELFDETG YPVDAVRANV
PAAELRMAIN PETNGGANQK ALRMPNYRDF AVEVRDGNMH QDMIEWGKYI AKMMELNPNN
FRGFGPDESK SNRLYAALDG SKRTWTADVH EPNDEDLAVN GRIIDSQLSE HQAEGFLEGY
TLTGRHGYFA TYESFGRVVD SMLTQHMKWM RKAKEQYWRN DYPALTFVDT STVFQQDHNG
YTHQDPGLLT HLYEKERPDM IGEYLPADTN TLLAVSDKIF REKEKINVLV TSKHPRQQWF
SIDEATELVA NGLGYVDWAS TDQGEEPDVV FAASGTEPTE EVFAAVELLH DAFPELKIRV
INVVDVMKLM TLDKNPEGMS DADFDRYFTA DKPVVFAWHG FRDMVQSLFF PRHNRNVHIH
SYIENGDITT PFDMRVLNEL DRYHLAKDAI LSVAGYEQKG AAFAQKMDDM VAKHNHYIRT
YGDDMPEVKD WTWKGLK
//
