ID A0A0R2I0N6_9LACO Unreviewed; 773 AA.
AC A0A0R2I0N6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:KRN58411.1};
GN ORFNames=IV45_GL000857 {ECO:0000313|EMBL:KRN58411.1};
OS Limosilactobacillus secaliphilus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=396268 {ECO:0000313|EMBL:KRN58411.1, ECO:0000313|Proteomes:UP000050934};
RN [1] {ECO:0000313|EMBL:KRN58411.1, ECO:0000313|Proteomes:UP000050934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17896 {ECO:0000313|EMBL:KRN58411.1,
RC ECO:0000313|Proteomes:UP000050934};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN58411.1}.
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DR EMBL; JQBW01000010; KRN58411.1; -; Genomic_DNA.
DR RefSeq; WP_057741739.1; NZ_JQBW01000010.1.
DR AlphaFoldDB; A0A0R2I0N6; -.
DR STRING; 396268.IV45_GL000857; -.
DR PATRIC; fig|396268.3.peg.869; -.
DR OrthoDB; 176168at2; -.
DR Proteomes; UP000050934; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06604; GH31_glucosidase_II_MalA; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR033403; DUF5110.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF166; ALPHA-GLUCOSIDASE; 1.
DR Pfam; PF17137; DUF5110; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185};
KW Reference proteome {ECO:0000313|Proteomes:UP000050934}.
FT DOMAIN 25..213
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 256..580
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 589..675
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
FT DOMAIN 692..744
FT /note="DUF5110"
FT /evidence="ECO:0000259|Pfam:PF17137"
SQ SEQUENCE 773 AA; 88731 MW; AA82330C9030FE41 CRC64;
MSNQLTGYEN NDQTITLTYE EGKPLILKVL TGEIIRVFQD HGVSANSYAV EGNKERKTKY
QVEDKGDHVE ITTSGLIVKA YDNQKLDVYD SEGNPLVIDY RGERTPLPTD MDDEHRHTVM
SEGHSVHAKA KAGNVNFEII KSLAPDEQFY GLGGKTGFLN KRGYEYDNWN ADNPVVHNET
QTHLYKSIPV VYGLKNGHPY GLFFDNSYKS HFDLGKESEH YYFYSAVGGN IDYYIMGGHT
LKDVVANYTY LTGVVPLPQK FMLGYQQSRW GYSTSDKRVE SIADGFAKYK LPIDVIHLDI
DYMNGYRDFT WDEKKYSNDT EGFVKRMHER GIRLMPILDA GVKKDDKYNI YKEGIEKGYF
VKNPDGSVYV GKVWPGDSVF PDFGNPDVRA WWAKHCKFFA DNGFCGIWND MDEPANFAQK
QLPNDTVFSN GHEKSTHARM HNVYGHLQAK ACYEGMKEAT GKRPYIITRA AYSGTQKYST
VWTGDNTAVW AHLAMAIPQL NGLGMSGFAF AGTDIGGFQE DTTPELLTRW IEASLFVPLF
RNHSIMGSRF QEPWAFDKQT LDIYRKYLNL RYRFIPFLYD QFRHETQCGL PVMRPLVLNY
DQDPAVRNLN DEYMVGSKLL VAPIVDQGQT KRLVYLPAGE WIDFWNNAEY SGKQSVVAEA
PIDKLPLFIK KDTILPWGNK VMHISDEPEK IMTFRLFGEA GSYVHYQDDG TDFNYQHGEY
NEYYVAVEEN GDVKVKLTNH GYKPTYQKIY VTTDQDRYEF DFDEKTGNYN LVK
//
