ID   A0A0R2PIW5_9ACTN        Unreviewed;       493 AA.
AC   A0A0R2PIW5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=NAD-dependent dehydratase {ECO:0000313|EMBL:KRO36715.1};
GN   ORFNames=ABR54_00555 {ECO:0000313|EMBL:KRO36715.1};
OS   Actinobacteria bacterium BACL15 MAG-120619-bin91.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetes incertae sedis;
OC   ac1 cluster.
OX   NCBI_TaxID=1655562 {ECO:0000313|EMBL:KRO36715.1, ECO:0000313|Proteomes:UP000053274};
RN   [1] {ECO:0000313|EMBL:KRO36715.1, ECO:0000313|Proteomes:UP000053274}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL15 MAG-120619-bin91 {ECO:0000313|EMBL:KRO36715.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO36715.1}.
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DR   EMBL; LIAM01000001; KRO36715.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2PIW5; -.
DR   Proteomes; UP000053274; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR021295; DUF2867.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR12126:SF11; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12126; NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED; 1.
DR   Pfam; PF11066; DUF2867; 1.
DR   Pfam; PF13460; NAD_binding_10; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        465..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..135
FT                   /note="NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF13460"
SQ   SEQUENCE   493 AA;  55254 MW;  1CBD8A9E20FD1BA3 CRC64;
     MNPHNEDRKY LVTGASGYVG GRLVRAFIDD KEDVRILVRD KNKIMGQPWA QLVDICEGSA
     ENFVDLQRAL EGVHTAFYLL HSINLGPHFD EIESEMARNF AKAAQEAGVS QIIYLGGIAN
     DKNISKHLAS REMTGKSLAT TSVAVLELRA GIIIGSGSAS FEMLRHLTHR LPIMTTPKWV
     MNKTHPIAIR DVLYYLKAVA HLDQPVNKVF DIGGPEVLSY ADMMQKFAKL SGLKKRWIIR
     VPVLTPGLSS LWIGLVTPVP TALARPLVGS LISEVVADPA KSIDALIPKP AEGLIDVENA
     IQLALSKITT HNVETRWSDA TMPTAPWQKA QGDPDWAGEM TLRDRRERIT DVSEEKVWRQ
     VERIGGENGW FGSDLLWWAR GVLDRFLVGG VGLRRGRRDP DFLRVGESLD FWRVEELEPG
     RRLKLYAEMV LPGKAWLEFT VTREYGKTKI VQEATFVPRG LGGQLYWYAV SPFHLFVFPT
     MLRNIVKKAK KDA
//