ID   A0A0R2PWU5_9ACTN        Unreviewed;       347 AA.
AC   A0A0R2PWU5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN   ORFNames=ABR67_03865 {ECO:0000313|EMBL:KRO42278.1};
OS   Acidimicrobium sp. BACL17 MAG-120823-bin42.
OC   Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC   Acidimicrobiaceae; Acidimicrobium.
OX   NCBI_TaxID=1655575 {ECO:0000313|EMBL:KRO42278.1, ECO:0000313|Proteomes:UP000051003};
RN   [1] {ECO:0000313|EMBL:KRO42278.1, ECO:0000313|Proteomes:UP000051003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL27 MAG-120823-bin42 {ECO:0000313|EMBL:KRO42278.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the histone deacetylase family.
CC       {ECO:0000256|ARBA:ARBA00005947}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO42278.1}.
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DR   EMBL; LIAZ01000173; KRO42278.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2PWU5; -.
DR   Proteomes; UP000051003; Unassembled WGS sequence.
DR   CDD; cd10001; HDAC_classII_APAH; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF9; HISTONE DEACETYLASE 8; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   3: Inferred from homology;
FT   DOMAIN          28..343
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   347 AA;  37849 MW;  267D29718EB64458 CRC64;
     MKVVYTDAHL GHNPQEEIAE SGSHSPHEHT VRAENIREVL QADASMSVVS PTQWGVDPIN
     AVHNPGLNNF LLSAWADYQR DVRPSREVVP DFFYRPSMRE AMSQLEEPTA TNARLGWWCF
     ETTTPITQGS YLAARGAVDT ALTATQIVLD GEKFAYGLCR PPGHHATTDL YGGYCFFNNA
     AVAAHYVAST NATKVTVLDV DYHHGNGTQQ IFYGRNDVQY VSLHGDPRRA YPYVTGFADE
     LGEGWGRGST TNIPLAAKTN DDMFLDSLDK ACAAIEAFGP SLLIVSLGLD TYITDPICDL
     AVTRDGFTRS GARVRGLNLP TVVLQEGGYD LANLGLNVQA WLHGLAS
//