ID   A0A0R2Q0H3_9ACTN        Unreviewed;       541 AA.
AC   A0A0R2Q0H3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   03-MAY-2023, entry version 17.
DE   RecName: Full=UmuC domain-containing protein {ECO:0000259|PROSITE:PS50173};
GN   ORFNames=ABR67_05115 {ECO:0000313|EMBL:KRO43767.1};
OS   Acidimicrobium sp. BACL17 MAG-120823-bin42.
OC   Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC   Acidimicrobiaceae; Acidimicrobium.
OX   NCBI_TaxID=1655575 {ECO:0000313|EMBL:KRO43767.1, ECO:0000313|Proteomes:UP000051003};
RN   [1] {ECO:0000313|EMBL:KRO43767.1, ECO:0000313|Proteomes:UP000051003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL27 MAG-120823-bin42 {ECO:0000313|EMBL:KRO43767.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC       untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC       forks, which arise in vivo from mismatched or misaligned primer ends.
CC       These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC       exonuclease (proofreading) activity. May be involved in translesional
CC       synthesis, in conjunction with the beta clamp from PolIII.
CC       {ECO:0000256|ARBA:ARBA00025589}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC       {ECO:0000256|ARBA:ARBA00010945}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO43767.1}.
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DR   EMBL; LIAZ01000028; KRO43767.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2Q0H3; -.
DR   Proteomes; UP000051003; Unassembled WGS sequence.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd03468; PolY_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR   PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR   Pfam; PF00817; IMS; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   3: Inferred from homology;
FT   DOMAIN          43..195
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
SQ   SEQUENCE   541 AA;  59077 MW;  B95A78AAA076B202 CRC64;
     MSVDVTRVAV VACPHWPAVA AQCELRSRGQ VIAAVAVVHA QRVIACTTGA IEHGVVVGMR
     KREAQATCPQ LHLVDHQPER DRLMFEPVVH AIAELVPLVE VSMPGVVVLA TRGPSRYVGG
     DDALAQRLTE IAHNALHQLA QGVRIPFGVG IADGRLTALI AAHSAAAVGE PRVVAQGQSQ
     QCLAVLPVSV LADFAEIDRS VVSLLQRLGL SYLGSIAQIQ PSILVGRFGP AGNEMQRLAR
     GLDRHPPIVI APPPEHASTH RFETPVEDVN VVVLTARQVA DQLVVHLGSH GASCVRLHIC
     LQTDHGEQSD RVWYQPEGLT AAAMAERVRW QMEAWVAQRA VTSGVVLFRL SPIGLRAREG
     RQLGLWGATT QADEAASRAI ERLTAMLGAE SVRVPEWRGG RDPSETFALT VAAVVDVEHR
     TQQTVRVQEH WHGALPAPSP SVVYDEPLPV MVCDALGNDV TVSGRHEMSA EPCVVVLQQQ
     HYTVLSWAGP WPVEERWWDT MRQRRIVRIQ LVVRRNNTAT TTRALVLTRE HGKWWVTSRF
     G
//