ID   A0A0R2SAF3_9FLAO        Unreviewed;       625 AA.
AC   A0A0R2SAF3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Transketolase-like pyrimidine-binding domain-containing protein {ECO:0000259|SMART:SM00861};
GN   ORFNames=ABR83_07085 {ECO:0000313|EMBL:KRO71790.1};
OS   Cryomorphaceae bacterium BACL18 MAG-120924-bin36.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Cryomorphaceae.
OX   NCBI_TaxID=1655591 {ECO:0000313|EMBL:KRO71790.1, ECO:0000313|Proteomes:UP000051105};
RN   [1] {ECO:0000313|EMBL:KRO71790.1, ECO:0000313|Proteomes:UP000051105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL18 MAG-120924-bin36 {ECO:0000313|EMBL:KRO71790.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO71790.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LIBP01000105; KRO71790.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2SAF3; -.
DR   Proteomes; UP000051105; Unassembled WGS sequence.
DR   GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          301..475
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   625 AA;  68740 MW;  8B8D83446992B785 CRC64;
     MYRAQGVDNG FSRKGAEVAW GTIGNASSSE GLFWETINAA GVLQVPMVAL VWDDEYGISV
     HAEHQTTKQN ISKILAGFQR QAATKGQVEE KGYEIIVARG WNYAELVAAF EQAEKVAREE
     HVPVLLHVRE MTQPQGHSTS GSHERYKSKE RLEWEQEYDC LRQFRLFLES NKIAKAKDLD
     ALEEAARAEV RDAMKAAFED FLQPLKRTRD QAVAWLEELG AEDLAAPLRA DKAPLRRDSV
     AAVRKAVQRR KADGLDALGA PLWVEAQLKQ AAHDYASQLH SGTALKVPAV APEFAPDAPQ
     VDGRVVLRDN FKELFTRYPE TMIFGEDVGH IGDVNQGLEG MQAEFGTVRV SDTGIREATI
     AGQGIGLAMR GLRPIAEIQY LDYLLYAVQI LSDDCATVRW RSAGGQKAPL IVRTRGHRLE
     GVWHSGSPMQ LLLGSLRGMY LCTPRNMVQA AGMYNTLLQA DEPAVVIECL NGYRLKEHLP
     TNLGSFTVPL GRPEILRSGT DATVVSYGST LRIVTDAATE LERFGISIEV IDVQTLLPFD
     LDGACVTSLK RTNRLLVVDE DVPGGAAAYL MQQILEEQGG YQHLDAAPRT LTAKAHRSAY
     GSDGDYFSKP SAEDVVEAVL ELVAQ
//