ID   A0A0R2SE13_9FLAO        Unreviewed;       496 AA.
AC   A0A0R2SE13;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Tungsten formylmethanofuran dehydrogenase {ECO:0000313|EMBL:KRO71586.1};
DE   Flags: Fragment;
GN   ORFNames=ABR83_01960 {ECO:0000313|EMBL:KRO71586.1};
OS   Cryomorphaceae bacterium BACL18 MAG-120924-bin36.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Cryomorphaceae.
OX   NCBI_TaxID=1655591 {ECO:0000313|EMBL:KRO71586.1, ECO:0000313|Proteomes:UP000051105};
RN   [1] {ECO:0000313|EMBL:KRO71586.1, ECO:0000313|Proteomes:UP000051105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL18 MAG-120924-bin36 {ECO:0000313|EMBL:KRO71586.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRO71586.1}.
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DR   EMBL; LIBP01000132; KRO71586.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2SE13; -.
DR   Proteomes; UP000051105; Unassembled WGS sequence.
DR   GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR   CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          347..496
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
FT   REGION          313..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         496
FT                   /evidence="ECO:0000313|EMBL:KRO71586.1"
SQ   SEQUENCE   496 AA;  53871 MW;  C38A6804EB2F739E CRC64;
     MKKGSALHAF ELMATAKAMA ELYEANKEVT ATYVHATARG HEAIQLALAT QLEPNDLLYP
     YYRDDAMLLG IGMTPYDLML QLLAKRDDPF SGGRTYYSHP SLRDADKPKI PHQSSATGMQ
     AIPAAGAAMG IQYREKQGLT AEWGGAKPIS VCSIGDAAMT EGEVSEALQM AALKRFPLLV
     LVQDNGWDIS ANAAETRSGN AAQYAQGFPG IDVVQVDGTD YAACHAALKD VLRTMRKKRG
     PVLVHAKVPL LNHHTSGVRM EWYRDDLDEA RARDPFPKLR AALLADGHKA AELDAIIDAT
     RARVQADYER ALEAPDPTPS DLYTHRLAPT PVTEERGTRE PAGRERTVMV DSALFAVREI
     LDAHPEALLY GQDVGRRLGG VFREAATLAQ QFGDDRVFNT PIQEAFIVGS TVGMAAVGLK
     PIVEVQFADY IWPGLNQLFT ELSRAHYLSN GKWTADMILR VPIGAYGSGG PFHSSSVESV
     VTAIRGIKVV YPSTGA
//