ID A0A0R2SH33_9ACTN Unreviewed; 210 AA.
AC A0A0R2SH33;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Malate dehydrogenase {ECO:0000313|EMBL:KRO72077.1};
DE Flags: Fragment;
GN ORFNames=ABS00_00060 {ECO:0000313|EMBL:KRO72077.1};
OS Actinobacteria bacterium BACL2 MAG-120920-bin34.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1655602 {ECO:0000313|EMBL:KRO72077.1, ECO:0000313|Proteomes:UP000051188};
RN [1] {ECO:0000313|EMBL:KRO72077.1, ECO:0000313|Proteomes:UP000051188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL20 MAG-120920-bin34 {ECO:0000313|EMBL:KRO72077.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the LDH/MDH superfamily.
CC {ECO:0000256|RuleBase:RU003369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO72077.1}.
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DR EMBL; LIBS01000276; KRO72077.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2SH33; -.
DR Proteomes; UP000051188; Unassembled WGS sequence.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.110.10; Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001557; L-lactate/malate_DH.
DR InterPro; IPR022383; Lactate/malate_DH_C.
DR InterPro; IPR001236; Lactate/malate_DH_N.
DR InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43128; L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)); 1.
DR PANTHER; PTHR43128:SF34; L-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF02866; Ldh_1_C; 1.
DR Pfam; PF00056; Ldh_1_N; 1.
DR PRINTS; PR00086; LLDHDRGNASE.
DR SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003369}.
FT DOMAIN 6..151
FT /note="Lactate/malate dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00056"
FT DOMAIN 156..203
FT /note="Lactate/malate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02866"
FT NON_TER 210
FT /evidence="ECO:0000313|EMBL:KRO72077.1"
SQ SEQUENCE 210 AA; 22026 MW; 135F49D46154951A CRC64;
MSRSGKVTVV GAGFYGSTTA LRLAEYDIFE SVVLTDILDG KPEGIALDIN QSRSIEGFES
RVIGATTTAE GKGYEATAGS DVVIITAGLP RKPGMSRMDL IGVNAGIVRG VAENIAKHSP
NAVLIVVSNP LDEMTALAQI ATKFPYQRVM GQAGMLDTAR FTHFVAEKLN VPVASVKTLT
LGSHGETMVP IPSRCTVDGA ALSTKLSDTE
//
