ID A0A0R2UB54_9GAMM Unreviewed; 354 AA.
AC A0A0R2UB54;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Methionine synthase I {ECO:0000313|EMBL:KRO96710.1};
DE EC=2.1.1.13 {ECO:0000313|EMBL:KRO96710.1};
GN ORFNames=ABS24_05875 {ECO:0000313|EMBL:KRO96710.1};
OS SAR92 bacterium BACL26 MAG-121220-bin70.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC Porticoccaceae; SAR92 clade.
OX NCBI_TaxID=1655626 {ECO:0000313|EMBL:KRO96710.1, ECO:0000313|Proteomes:UP000051213};
RN [1] {ECO:0000313|EMBL:KRO96710.1, ECO:0000313|Proteomes:UP000051213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL26 MAG-121220-bin70 {ECO:0000313|EMBL:KRO96710.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU00333};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO96710.1}.
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DR EMBL; LICA01000042; KRO96710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2UB54; -.
DR Proteomes; UP000051213; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008705; F:methionine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.330; Homocysteine-binding-like domain; 1.
DR InterPro; IPR003726; HCY_dom.
DR InterPro; IPR036589; HCY_dom_sf.
DR PANTHER; PTHR11103:SF18; HOMOCYSTEINE S-METHYLTRANSFERASE 1-RELATED; 1.
DR PANTHER; PTHR11103; SLR1189 PROTEIN; 1.
DR Pfam; PF02574; S-methyl_trans; 1.
DR SUPFAM; SSF82282; Homocysteine S-methyltransferase; 1.
DR PROSITE; PS50970; HCY; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00333};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00333};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00333}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00333}.
FT DOMAIN 3..297
FT /note="Hcy-binding"
FT /evidence="ECO:0000259|PROSITE:PS50970"
FT REGION 329..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 212
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00333"
FT BINDING 282
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00333"
FT BINDING 283
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00333"
SQ SEQUENCE 354 AA; 37109 MW; 99C4D6EC4D290F33 CRC64;
MDNIFLRLLD EKQTLLIDGA TGTNLFALGL QSGDSPEFWN IDFPDRVASH YRSFIGAGSD
IVLTNSFGGN SYRLKLHDAQ DRVAEFNRAA AQILVKEVAA SGRDVVVAGA MGPTGEIFAP
AGLMTIEEGE VAFAEQAIAL KAGGADILWI ETLSSIEECH AAVRGASVAE LPIVLTLSIE
TNGRTMMGIT PSDLVQLQTE LCTPLAAYGT NCGLGAAEVI AAIINMRQAA ELAGVEPILV
AKGNCGIPEW VDGEICYSGT PELMASYTQM AMDAGARIIG GCCGTSPEHV AVMRQAMDRH
TKGVTPDLER IQSELGVITS GAKAQMGGDL SIAGGAAGPG HKASSRARRR QNPH
//
