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Database: UniProt
Entry: A0A0R3NKR0_DROPS
LinkDB: A0A0R3NKR0_DROPS
Original site: A0A0R3NKR0_DROPS 
ID   A0A0R3NKR0_DROPS        Unreviewed;      2131 AA.
AC   A0A0R3NKR0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   07-JUN-2017, entry version 12.
DE   SubName: Full=Uncharacterized protein, isoform N {ECO:0000313|EMBL:KRT01467.1};
GN   Name=Dpse\GA15628 {ECO:0000313|EMBL:KRT01467.1};
GN   ORFNames=Dpse_GA15628 {ECO:0000313|EMBL:KRT01467.1}, GA15628
GN   {ECO:0000313|FlyBase:FBgn0075645};
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245 {ECO:0000313|EMBL:KRT01467.1, ECO:0000313|Proteomes:UP000001819};
RN   [1] {ECO:0000313|EMBL:KRT01467.1, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P.,
RA   Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J.,
RA   van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E.,
RA   Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D.,
RA   Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D.,
RA   Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R.,
RA   Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L.,
RA   Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura:
RT   chromosomal, gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
RN   [2] {ECO:0000313|EMBL:KRT01467.1, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CM000071; KRT01467.1; -; Genomic_DNA.
DR   RefSeq; XP_015039029.1; XM_015183543.1.
DR   GeneID; 4803359; -.
DR   FlyBase; FBgn0075645; Dpse\GA15628.
DR   Proteomes; UP000001819; Chromosome 3.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR032415; TRPM_tetra.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001819};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001819}.
FT   DOMAIN      917   1259       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1350   1405       TRPM_tetra. {ECO:0000259|Pfam:PF16519}.
SQ   SEQUENCE   2131 AA;  236344 MW;  02CD8ECC74560C53 CRC64;
     MLKQKRLAKQ KPKAKPIPWG LKKICWGLIN ITVPRHQPRS WIETNFQKRE CIKFIPCPKD
     DTRCCCGQAQ ITHQTIQGIE SGSPGDLWLP TKHTRPQPTD AYGTIEFQGG AHPTKAQYVR
     LSFDTRPELL VQLFTKEWNL ELPKLLITVQ GGKANFDLQA KLKKEIRKGL LKAAKTTGAW
     IFTGGTNTGV TKQVGDALLL EGQQRTGRVV SIGIAPWGIV ERNHELLGHN REVPCHSISS
     PRSKLAVLNN RHAYFLLVDN GTQAKYGAEL ILRRKLEKFI SNLKLHPFTH SSTPVVCLVI
     EGGTNTIRAV LEYVTDSPPV PVVVCDGSGR AADLLAFVHK YASDGEEQPV LESMRDYLIG
     TIQKTFEVGL DQAEKLYQEL LQCTRNKNLI TVFRIQEKPE GEAQELDQTI LTALFKSQHL
     SPPEQLSLAL TWNRVDIARS EIFVYGQEWP HGALDEAMMQ ALEHDRIDFV KLLLENGVSM
     KKFLTIPRLE ELYNTKHGPA NTLGYILRDV RPHIPKGYIY TLHDIGLVIN KLMGGAYRSY
     YTRRKFRPIY AKVMNSYANA CRKSSTYQYQ RYAGANSLSL VTGLLPFTSE MALFEFPFNE
     LLIWAVLTKR QQMALLMWTH GEEALAKSLV SCKLYKAMAH EAAEDDLDTE IYEELRSYAK
     EFESKGNKLL DFSYRQDAEK AQRLLTCELH SWSNQSCLSL AVAANHRALL AHPCSQVILA
     DLWMGGLRTR KNTNFKVILG LVMPLYIRQL DFKSKEELQQ MPQTEEEHLE NQNLDNDDSD
     RSQPDAESAL LKAKRSISLR YRMGANTYNR EKCKLIAAET SSPSYKSAAN STDALLADTY
     SVRDTKVHEN GKVNLTAGAE EPPSNVSLTD SDPAQFREFF NLSEYNEIKQ HQPLRLKKKF
     HEFYTAPITK FWADSIAYMF FLIMFSFTVL VKMGPVPRWQ EWYSIAYITT LGFEKVREII
     SSEPVAITHK FSVWAWNMWN PCDGAAIILF LIGLAFRFRP NTMDIGRVIY CVDSIYWYLR
     ILNILGVNKY LGPLVTMMGK MVKNMIYFVV LLAVVLMSFG VSRQAILYPN SEPTWRLIRE
     VIAGSIVAPG FPGALGHSSR SHNARGGGYG STFSPGSFAA GYHRGHATAS SPTATATTTT
     TTSTVRPLSS ATATAPETGS AATPAPHAPT GTTFNSSEHG HLSGGNLTNV TYQPYFMLYG
     EVFADDIDPP CGEDPRQPAC VTGHWVTPIT MSMYLLIANI LLINLLIAVF NNIFNEVNSV
     SHQVWMFQRF TVVMEYQQKP VLPPPFIAFC HFYSLLKYCV RKAKGLEVQR DNGLKLFLEK
     DDLERLYDFE EECVEGFFHE QEIILNQSTD ERVKNTTDRV ETMSQKIEDI NQKENIQTAT
     VQNIEFRLRK MEESSEQILS HLAVIHRFMS THTVGTDDMR GSAINIPAEI HRIRTISMSD
     TDGGGGSSGN GGGGGGGAAV PLVLGAGLNV NSLQVTNRRR FNRSLTEVRP DAYILDEGTH
     FEVVPLPEEP DEVVKSREAL NEQVVRKASM QSEADSDIYL PLSQRPSTCE TVKRTPYVTV
     RQDTGASTES KDTLTPLGTN DDDQTLVGGD NSDDAAPDIN FEAARHRALR QRTVSLCRRN
     SETYSLAGAD INRSHISLNQ LTMLSRRQMS LTQSEPDSDK DAPPAAAGST HPGKSVLHAK
     PSRNILLKLH SEYTSITDEL ESVCHMIASP TVSLQSNKAS LDRPKTEMSR AEAAALQEKK
     HLKECEENDY RILEGLFEAR GSIDASAEAF ESVISVDYSH RYPLRRETAV ELSPSKPSAE
     VDLMGGGGGG GDSSDTSGAG SCSAMGAVSS GFQLKNERPW QRNSSMEQQT YPSPLVPSRA
     TSDFLNPPFE SSGRLFKKSS ESLQKNSSTE TDYSAHPYRF IKQSSNETNT SLTGSYNVDT
     PSLTAEPSLD ACDSHSATGI SISVGAAGGS AARYQPIRTT SIGAADGRQL RDESSSSLQS
     PELGVQCSAP VTMQAPPAVP TRPMLLKKQF SLDKGKPQQA QITAEAMATP ESGIDAATVA
     QARVKLISSL KPQSHTSKLG MNVLKESSSS TEGSREGEGL STTSSAKNSN PALSIPQIST
     HLVQDEIAKL SSNIKSSTES EKDPPYNETM C
//
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