ID A0A0R3PDR5_ANGCS Unreviewed; 476 AA.
AC A0A0R3PDR5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=ACOC_LOCUS2117 {ECO:0000313|EMBL:VDM53702.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000211601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0000211601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM53702.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM53702.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYA01000384; VDM53702.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3PDR5; -.
DR STRING; 334426.A0A0R3PDR5; -.
DR WBParaSite; ACOC_0000211601-mRNA-1; ACOC_0000211601-mRNA-1; ACOC_0000211601.
DR OMA; FEHRYHA; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF4; SERINE_THREONINE-PROTEIN KINASE PAK MBT; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00285; PBD; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT DOMAIN 16..29
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 205..456
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 152..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 234
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 476 AA; 53222 MW; 32A399AD0C24CEE3 CRC64;
MNRTFSMRKK LKKSEISTPS NFEHRIHAGY DARTGTYTGL PKQWQALLGP PRSLNGRPRP
IVDPSCITPV DIAELKTVIR GAGSRSTGFF SSMNTSFHCV TVARSNSLRT TTTALRPPSV
KSPVKVHGYP FNDPNYAPLP LKLPTVTTFG SSPHSITSDT QISPNSTVTS SITSPEKASN
EGVGYDEFRV ALSCVVDRRD PQTDLTNFTI VGEGSTGIVF AAYKKSTRQT VAVKRMNLRK
QQRRELLFNE VSIMRDYQHA NIVRMFSSHL VGDELWVVME YMEGGSLTDI VTQTRMTEAQ
IATVSQQVLK GLEFLHARQV IHRDIKSDSI LLRRDGTVKI SDFGFCGHLS DEFPRRRSLV
GTPYWTAAEV IARQPYGTAA DIWSFGIMLI EMVEGEPPLF NEELFQAMKM IRDNPPPKFN
PTANVSPELA HMLSRCVVKD PTQRATAIEL LRHPLLRTVQ HHSCIAHLIK NNRDGK
//
