ID A0A0R3PJX0_ANGCS Unreviewed; 315 AA.
AC A0A0R3PJX0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=L-gulonate 3-dehydrogenase {ECO:0000256|ARBA:ARBA00038962};
DE EC=1.1.1.45 {ECO:0000256|ARBA:ARBA00038962};
DE AltName: Full=L-gulonate 3-dehydrogenase {ECO:0000256|ARBA:ARBA00042709};
GN ORFNames=ACOC_LOCUS4808 {ECO:0000313|EMBL:VDM56393.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000480701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0000480701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM56393.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM56393.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYA01003831; VDM56393.1; -; Genomic_DNA.
DR STRING; 334426.A0A0R3PJX0; -.
DR WBParaSite; ACOC_0000480701-mRNA-1; ACOC_0000480701-mRNA-1; ACOC_0000480701.
DR OMA; RDNCLTH; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT DOMAIN 7..185
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 191..245
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 315 AA; 34868 MW; 1EE95826C24B7711 CRC64;
MSESKGKVAI IGSGLIGTCW ATLFVSAGYT ICLYDISQNQ LESSRQTILK NLQTLINDGL
SRGDITVAVA QKRITTTSTL SEALIGAIYA QESTCEDVEF KRKIFAEMDL WASSDTILAS
STSTIPASTF TGSLSHRSQS LVAHPVNPPL YLTLVEIVPA PWTSDPVVRR TYEIMKDIGQ
EPVRLHHEVL GFAVNRLQYA LLAEAWRLVG NNVLSPEDID KVMIAGLGPR YAIHGPLQTV
HLNANGIRDY FFRYGEGIRR VLADFGATPT FKEADVLEKL ETSLNKSMPL DQLRTKKAER
ERNLALLKSL KKKME
//
