ID A0A0R3PZL3_ANGCS Unreviewed; 325 AA.
AC A0A0R3PZL3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DH domain-containing protein {ECO:0000313|WBParaSite:ACOC_0001201001-mRNA-1};
GN ORFNames=ACOC_LOCUS12011 {ECO:0000313|EMBL:VDM63596.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001201001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0001201001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM63596.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM63596.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UYYA01004864; VDM63596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3PZL3; -.
DR STRING; 334426.A0A0R3PZL3; -.
DR WBParaSite; ACOC_0001201001-mRNA-1; ACOC_0001201001-mRNA-1; ACOC_0001201001.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR026817; Ect2.
DR PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT DOMAIN 67..255
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 37021 MW; 43AD8882FB6A7803 CRC64;
MLGPKPFKSV PASETQNSPE TTGVKENPSE LDENTCVFTL AFDLRKKISL GVDSTATAIL
SDGASDGMYL VCKEIYTKES RLIGKLKLLL TVRDGLLDRV AQKRPLLKSE QIAQIFGRVQ
GQLRFHEKIC EKLGKIIENW DGSVCDVVRI WTETFDEHRR VYSSYTNYYD RATAMLKNAC
EKDPKLKKFF EGQEKNKLFE RKRVVDVMIE PVQHVPGLKN ILERLEKVDR EQGGNNPIGE
AIVTIEKILS YSNNVLMNNE VGMKKLILIK EIEDLPPDFL KGSNVMLCSL EVRWICAEKK
LKIEKDDTVK LILFNDSTVL VSRFC
//
