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Database: UniProt
Entry: A0A0R3QJC6_9BILA
LinkDB: A0A0R3QJC6_9BILA
Original site: A0A0R3QJC6_9BILA 
ID   A0A0R3QJC6_9BILA        Unreviewed;      3602 AA.
AC   A0A0R3QJC6;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   25-OCT-2017, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:BTMF_0000742501-mRNA-1};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida;
OC   Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000742501-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000742501-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:BTMF_0000742501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
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DR   WBParaSite; BTMF_0000742501-mRNA-1; BTMF_0000742501-mRNA-1; BTMF_0000742501.
DR   Proteomes; UP000050602; Genome Assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR035910; IP3R_RIH_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 4.
DR   Pfam; PF08709; Ins145_P3_rec; 2.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050602};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050602};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      104    158       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      190    234       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      243    298       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      358    416       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      595    816       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1039   1270       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1576   1782       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   3602 AA;  407564 MW;  F0B31A49DF906495 CRC64;
     MTDKEGTGDG EQDDISFLRT GDIVAMTCMA SASREGVLGS ERVCLCTEGF GNRMCSLENV
     SDRDLPADIS MCMLYIDNAL SVRALQEMMS NDKELRGAGS GGGHKTLLYG HAVQLKHVQS
     EMYLACLSSC SSNDKLAFDV GVQENNDGEA CWWTIHPASK QRSEGEKVRV GDDVILVSVA
     TXXXXXXXXG EKVRVGDDVI LVSVATERYL HMTHSKGFMV IASFHQTLWN ITSVSSGSVR
     IRNMGALFGN DVLRFFHGND EVLTIPENWS EHPQQNMAIY EGGAAVSQAR SLWRIELIRI
     KWHGALVGWE QPYLGVMENV IQLYDKDKAE FDTTAFVMYQ TKDLKKQLLE EKEEGMGVAT
     IRYGETNAFI QHIKTELWLS YQTSETTKKG LGKVEEKKAV ALKDGHMDDC FTFFMALEEE
     SKSARVIRKC SSVLNRFLRG IEALQREGKQ AQDWNRVDLS EVLKLMEDLI DYFAQPDEDD
     FEASQNRLRA LRSRQDLFQE EGVLNMILDT IDKFSQMEAV RDFAGLLNED TQMMWEEIST
     YLYLLVAAMI KGNHYNCAQF ASAQRLQWLF GRLSNPQSAE GILDVLYCVL TESPEALNMI
     NESHIKSVIS LLEKVGRDPK VLDVLSSLCE GNGMAVRSSQ NTITQYLLPG KDLLLQTKMR
     DHVSSMTPNI LVGVVEGSSQ FRRWYYEAEV EHIERMTKTE PYLRIGWANS MGYKPFPGSG
     DGWGCIGVGD DYYSYGFDGR CIYCATKKHV IWTRTLQKGD VVGCLLDLNI PEISFTVNGQ
     STAGMFKNFN IDGFFFPVMS LSAKVSCRFM FGGIEGRLRF GPPPGFSALI EAAANKLEIG
     ECVSFGDIAK NVYTGPSILR QNTEPFVPKL VDISAVVLPH FAMEIHEKMA ENLHELWAMR
     KIELGWSYGE VRDEKTRRHP CLTSFQQLPP NEKAYNINLA IDTMKTIEAL RYHMILDEPP
     VRLRPVRLPQ NYQQSNGFKP QPLDCHEIVL DDNMFSLIDA LAKNTHNVWA REKIRRGWTF
     GLNEKHLLLQ FVNISQKRSP HLVPYEVVDQ RIKEANRESA TEFIKTLQLF GIFLESPVLE
     HDEGAEKELK VTKAFSRTYR AEALYAVSSG KWYFEFEVLT SGFMKVGWMD IXXXXXXXXX
     XXXXXXXXXX XXFEVLTSGF MKVGWMDISA QSTVDIGTDD RSYGFDGYLA RKWHQGAGTY
     GREWKIGDIV GAFLDLSDHT ISFSLNGELL LDPSGSEMAF DNVLVTDGFV PAMTFSAGQR
     AKLNFGQDSN SLKYFTTCGL QEGYEPFCVN MYRQMPMWYA KRLPQFEDIG LNSTIEVSRI
     PATGNNPPCL KITQKEIDTG DMTAQEKAKM EYIRLSLPVK CNEKLQPTKD KESIMRSLHE
     IEKQLAEEAQ PVPTIRHPAI PKEFGDDTKV NKASISTIAP AYCDLSASSY ICSMHNLYHI
     KSLGRSLLSA FKHSAEEDES SARSKPISFD GDHHLAETST IRMSGSMLEL SSTGEQRDGK
     HKRGGLMARF HQRKKEGMSS ENKRTTGMLV DGHIVSVDTI SAENIPPSMS KDDQDMPQSG
     PGRSRRGLMG SDKWKKKNEK FLEHRRPSIA ALEQSVIIDG NVPSDDVXXX XXXXXXXLEQ
     SVIIDGNVPS DDVRTMIELG DKIDEFYYAI RIFPGQDPAN VWVGWVTPKY HFYAERFITG
     EAIRRCKYQG TSENVNEGES XCYVVNAAEL LQSVPEPGNT KVSGLLIGCI IDTSVGELSF
     LASKQDTGFR FKLEPGAILY PAAFVAPTSA EVLQFELGRI KYTFPLSSAM FKSSHKSLLP
     FCPPRLTVEK LNPVHWARVP NECLRTTALK LSDFRGWSVL CDDPVRIMSI YIPEKDTSYD
     ILEMIEHNDL LTFHRQTLNL YCKLAAHGNQ KVAHILCSHV DEDQILYAVK SHYLSGPLRQ
     GFHDFLIAVH LRTYVNARQS TTHEYVIPLK QNHEIKNVFH PEIEDRFPQI LGPTISIRPV
     IVCSKVRSNF GMDAESKLLP PAFNFVALKA HVMSALSSAT EHAVISCRDL IGGNCLNHFE
     PLFKLFNALL VIGIFDDDDL KDVMKLIHPI AFDENYVPGL KQKGLTEIEL AEGVKIQLTI
     ILENICNIQL RHRVESLVSF AAGFVNDLQQ DQFSRYMSIK QTNMTPAEAA RRTKEFRCPP
     REQMFRLMKC KAVPDDSIGI MLDDETEYDQ CPMNETLQQQ LRQFCSLLVG RVGCVKSEER
     NKLSELVILE EANSWVDQLA QLVIRVPPPF TGEDKSMNHN GTESFRLMIC TMLKSWATSS
     VIESNELIRK MFSLLLRQYT GVAEMMKALS QTYVLHERNI EDVQDFIENL VQVRELLSVQ
     FESAEEAILK RGLWKLMNNR IFFQHPDLMR LLTVHENVMS IMMNVLTAQQ GATNHGEHTE
     HVENMEEIVN AQDSKDASEM VVACSRFLCY FCRTSRQNQK AMFEHLSFLL DNATMLLARP
     SLRGSVPLDI AYSSFMDNNE LALALKEEEL DKVTVYLSRC GLQPNLELVA KGYPDIGWDP
     VEGERYIDFL RFCVWINGES VEENANLVIR LLIRRPECLG VALKGEGQGL FSAFKEAIAL
     SEDIRTLEEN KNRAVIHSAL LREQPHYPNK ETEGEDYVDL GAATLDFYSS LVDLLAKCAP
     DKINIQAGKG DCMRARAILR SLISLDDLGQ ILALRFTIPN LITSVATDDV GPLPGLLPNH
     KQSVLLFLDR VYGIDSQEML FHFLEKSFLP DLRAATMMDS PCSVESDTAL ALNRYLCNAV
     LPLLTSHSYY FADAEHHAAL LDTTLHTVYS MNHLRSLTKN QRDAVSDFLV AITRELPPPM
     MVKLMRKVII DIQEMDENLL VPLRILTLHY ERCTKYYGSG NIYGMASETE KRLSMLLFYA
     IFDSLGSKQY DPELFGKALP CLTAIGSAIS PDYTLTTTGD DTDRIQKTKD RGIWNPDPVD
     VSEVHFDDDL KSVVAKFAEH FHDSWASRKI EKGWNYGELY SRQALTHPRL KPFVFLPDFE
     KNFYQERCAE CLRALLVWNY SIELTDRDAA DKAIQNNTSL EVNSLQFAVE NFNPKPVDLS
     NMTLEKDMTG IAEKMAEESH KIWAKKVLAD LNRGGTMPPQ LVPWDLLTDF ERRKDRFRAA
     EILKFLQYHG YRVWSSNKPE PSAERVKIDS ERSSVEKRFA YNLLKKLIQY LEQASLKMKT
     IKPSQELTRQ NSFRKEGQDV KFFEKVVLPL MHAYFNAHKN YFLANSSVVQ TGMASDKEKE
     MVANLFCRLA SLLRFKNHAF GNVAKITVRC LQGLIQSLDL RTLVKINSDI VRTGLLTFFN
     NCADDLFSAV EELQNGGQYS LLRGQNLKSW VSLEFANQMI IPVLTTMFVH LAINHFGSDL
     LLDEIQAACY KILDSAYLLN SLAATTSQRK SIAYEMDKHR PALGQCLAAF AGCFPVAFLE
     DKFNKNNKYS LLAKSQDQSV QVQEMLQNLL AHIPQLDKLL TEVEQVGQSG AMYREQPAAY
     DVDLPLICSY LTYWWQLGPD SSNRSTVPVT DVGNEHINRI FRALLQMIHN HIGVENASWL
     CRINFFSVQI IPYVSCDAVK DYMLPVAERL RRLAEKAYRE EEHMRTHPDD ADEGTVAEVT
     VK
//
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