ID   A0A0R3QVH6_9BILA        Unreviewed;       792 AA.
AC   A0A0R3QVH6;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:BTMF_0001173401-mRNA-1};
GN   ORFNames=BTMF_LOCUS9762 {ECO:0000313|EMBL:VDO33072.1};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0001173401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BTMF_0001173401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO33072.1, ECO:0000313|Proteomes:UP000280834}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UZAG01017144; VDO33072.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R3QVH6; -.
DR   STRING; 42155.A0A0R3QVH6; -.
DR   WBParaSite; BTMF_0001173401-mRNA-1; BTMF_0001173401-mRNA-1; BTMF_0001173401.
DR   Proteomes; UP000050602; Unplaced.
DR   Proteomes; UP000280834; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR   CDD; cd06366; PBP1_GABAb_receptor; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR002455; GPCR3_GABA-B.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR   PANTHER; PTHR10519:SF76; GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   PRINTS; PR01177; GABAB1RECPTR.
DR   PRINTS; PR01176; GABABRECEPTR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        394..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        519..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        574..593
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        605..630
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        636..658
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          394..669
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
FT   COILED          693..727
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   792 AA;  89611 MW;  044DA27B98E09C7B CRC64;
     MLKLHYHNSK CQPGLAAKQM YELLYKAPTK LMLLAGCSPV TTVFAEAAPV WNLVVLSYGG
     SSPALSNRQR FPTLFRTHPT ANMQNPTRSK LRLFQKFKWK KITILQSVEE VFTSTAKDLE
     EQCREKGIRE QCREKGIRVE RQSFYGDPSD AVKTLVRQDA RIIVGLFYVT EARRVLCQAY
     KHDLYGRKYV WFFIGWYADT WFIPPTDEPL NCTAEQMIKA AQYHITTESI MLSRDEELTV
     SGMTGKQFQN RLMSMLTTDP AETGGFPEAP LAYDAVWAVA LAFNCTLSKL QVGQSLENFA
     YNNTSIAKKL FSCVKDTQFR GVSGQVMFND LGDRIARTQI EQLQDGKYQM LGIYDTTTLH
     LDWYDKEKFS TMNGLPPPDS TLIQEWLLTV DLELYYAIAL LAVIGIFVAC IIFIFNVKNS
     DRVIIMESQP QCNNVLLAGC ILCCLSLLLL GLPARGITVP KHSFTLLCHS QISLLMVGFT
     FAYGSMFAKV WVVHRLGSTE NQHLISKPTT GQPVPACKFY LVVTAFFVVD IIIIACWFTF
     DPIQRVEQRF PLQEPPMGTE EDIMLLPILE LCQSLVMGYK CLLLVLGLFL AYETRNLKPL
     FVNDLRFVGL AIYNVAVLSL ITGPIVTFLI RSQSDANFAF ISITVLLSTY ITLGLIFLPK
     IVHIRRIPKS GEKNDGTKPL YHPVDAGIEQ KRCQQLVHEN ADLKCQIEHK EKKIADYQQR
     LGKHIQETTG IPLRERLCGS TSDENITQSF PTALTTTALI ENLPSENMAK HNSNYEEVEN
     EDTSSTFSEL FL
//