GenomeNet

Database: UniProt
Entry: A0A0R3R2V9_9BILA
LinkDB: A0A0R3R2V9_9BILA
Original site: A0A0R3R2V9_9BILA 
ID   A0A0R3R2V9_9BILA        Unreviewed;       552 AA.
AC   A0A0R3R2V9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   12-APR-2017, entry version 5.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida;
OC   Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0001434901-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0001434901-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:BTMF_0001434901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361189}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   WBParaSite; BTMF_0001434901-mRNA-1; BTMF_0001434901-mRNA-1; BTMF_0001434901.
DR   Proteomes; UP000050602; Genome Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050602};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050602};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    381    406       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    418    441       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    518    546       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       51     82       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   552 AA;  63747 MW;  5C847EDEF36FEDEA CRC64;
     MSSLQRRFVG DLKRCDLLAQ KLKFIEEQIL ADSIPIPRLN EFVPAPRPSE MNTLETEIEE
     IEEQLLENNK NMKNLMNNYA QLNECMQCIN KVQQLLTDGQ RQQARQSLLG MENPTSGIGA
     IRRKLTNVMI GRKDSIIPDR MSSIFSGENF VAGIVERCHS TALERLLWRT CGLNVFVRTV
     TIDFSEDPLL NDITPKDVFM VFFSGAVLGL RVRKICKCYQ AKIYDYKDPA NNRVLHVTSL
     FGRVAEIKSI IEETRKYRNT LLRAAAFKAH EWDIKLQKMT AIFMVMNMCN VDITQRYLIA
     ECWIPTADII RVRKNFDKTG MLAQEKNGYV FLCQIETNKV PPTYFRVNKF TKIFQSIVNS
     YSIATYREIN PAPWTMITFP FLFAVMFGDA GHGLIMFFVA LAFILFENKI KIDDEIMGSF
     YCGRYIILLM GLFSIYTGFI YNDFYSRSMN LFGSSWYNPY KSSLLELTPV DMQFDLILPP
     QYAYDRDKGP YVFGLDPVWN LAENRLTFTN SMKMKASIVF GIIQMTFGVI LSLMNYLFVS
     VLLVVISFQK KQ
//
DBGET integrated database retrieval system