ID A0A0R3SIV4_HYMDI Unreviewed; 534 AA.
AC A0A0R3SIV4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=EGF-like domain protein {ECO:0000313|WBParaSite:HDID_0000486901-mRNA-1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000486901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000486901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A0R3SIV4; -.
DR STRING; 6216.A0A0R3SIV4; -.
DR WBParaSite; HDID_0000486901-mRNA-1; HDID_0000486901-mRNA-1; HDID_0000486901.
DR Proteomes; UP000046397; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 4.10.470.20; -; 2.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR035993; Notch-like_dom_sf.
DR InterPro; IPR000800; Notch_dom.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR PANTHER; PTHR24044:SF498; PROTEIN EYES SHUT HOMOLOG-RELATED; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF00066; Notch; 2.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00004; NL; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF90193; Notch domain; 2.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 9..57
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 59..96
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 97..134
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 192..228
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 47..56
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 86..95
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 124..133
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 218..227
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 534 AA; 58921 MW; E80EFB7DAC96ADE4 CRC64;
LSSFLPDAAS KACDAQPCKN GATCRERVIP QSIYFEPQSL LPYECDCTFG WEGENCTVNV
DDCKGNPCLN GGHCEDKPNA QFVCHCRDGF IGQKCEFRDP CLDFPCQNSG RCDSSPLGVY
QCICPRWYEG QNCEKVKMPC ESSHNQCRHG KCETLYEVYE ARVQNESKKA SRISGFRCNC
EPGWTGIFCD RAFNICQYHQ CQNNAQCVSL GDHYECKCPI GFGGELCERP NSQSTKKRDT
QINMEEQCRL LGCTSEANGT CSGRCVQAGC FNQEQLNACR DWIDCLEATK LEFGVGQPSC
VERYRDGVCD YECAISSCFY DGFDCTDSGS SCPTAEFCTS VYRDGTCHLV CNTPVCGFDG
GDCLNIQDQL HPQIDNIRTG YIGLVLDANK TTYFQMERII MARVADVLRA VVRPVIDEKT
QQPIVVEMDE GTRIQVAFII DLLPEGFHGS PGEIYESVNQ AAHTLKAALD RGALDLPIPV
AQLWVANDPL APPPGSSSSN TPGGLPFLRS KDAIGLYIVL CVLSGVHKTF CGTY
//
