ID   A0A0R3SQ39_HYMDI        Unreviewed;      4346 AA.
AC   A0A0R3SQ39;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Chorein_N domain-containing protein {ECO:0000313|WBParaSite:HDID_0000716001-mRNA-1};
GN   ORFNames=HDID_LOCUS7158 {ECO:0000313|EMBL:VDL59476.1};
OS   Hymenolepis diminuta (Rat tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX   NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000716001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HDID_0000716001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL59476.1, ECO:0000313|Proteomes:UP000274504}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC       {ECO:0000256|ARBA:ARBA00007965}.
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DR   EMBL; UYSG01010909; VDL59476.1; -; Genomic_DNA.
DR   STRING; 6216.A0A0R3SQ39; -.
DR   WBParaSite; HDID_0000716001-mRNA-1; HDID_0000716001-mRNA-1; HDID_0000716001.
DR   Proteomes; UP000046397; Unplaced.
DR   Proteomes; UP000274504; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002259; Eqnu_transpt.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR026854; VPS13-like_N.
DR   InterPro; IPR031645; VPS13_DH-like.
DR   InterPro; IPR039782; VPS13B.
DR   PANTHER; PTHR12517:SF0; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B; 1.
DR   PANTHER; PTHR12517; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B; 1.
DR   Pfam; PF12624; Chorein_N; 1.
DR   Pfam; PF01733; Nucleoside_tran; 1.
DR   Pfam; PF16909; VPS13_DH-like; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          8..108
FT                   /note="Chorein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12624"
FT   DOMAIN          3494..3622
FT                   /note="Vacuolar protein sorting-associated protein 13 DH-
FT                   like"
FT                   /evidence="ECO:0000259|Pfam:PF16909"
FT   REGION          104..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   4346 AA;  483121 MW;  60072428D1FB1CB0 CRC64;
     MQKIFSIETY LGPLLMRYIG KYVKLRDDQF QLSLWGGDAV LNYVELQYDI FEDLMPLPIG
     FKSGHIHELR IQVPWTRLGS SSIVITLNTV ECVLAFKQPG ESHRRKSEAT SVPSADALNP
     SLDTPPPPSY LQSYLTRIWS NIEVVVSNLI VKFEEADAVI SLNIRSLDCF PTLPNWQRGI
     ENPSTGNYCL HRLLKFTDIT LCVDRCDVKG RISAYQDPVI YRHSFEIRLQ TIFTQKSSGL
     ASICVANLYN PKLIELNLSQ VQIPLITRLL EILLALSNKI LKWDALSDSQ VLGTQEIDAK
     MTNVVDEGVD TDPSQSQSWS QWVWSFVPSI PSFSSNLSDE EIFDYELDES GLEYLDGLET
     CNARAEYIKL LYDDALSSSS ETAKFRRAQL FRLRKHHQLI PVLILGVLMK KIQINIKTVQ
     RLNRSESIPS QTSSAKNLRR NEPMHDMLYL SIENLGFQCV QDAGHFASVQ CGFGVLRITP
     AGEICPCGRK DAPLDSFPCL LEIQSKINGV DEKENSDKLL RTFCGLFERN ELNSTGFICE
     QESDAQKEVV SSQPTLTNSY ILPPFCRKHY LSSYGSDYPQ NKLPLGIWFD TVSCKESENE
     GIDDNYENLP TGPVQYSFGR FLLDSVKVNF TLSISHRIQH FLRILADGSR HYKPCADWVA
     LDVIPPQEPV DSWILQERMV HLRQFTPLSI SRAQVLSLCV EVFPPVHGRS DDSLSSLKFE
     VDKIEALDST PLDRVQLIFT MTHLYPSSGV ISDVNSSFRK DLVRNDPLEC KSWGRRDQIS
     ACFGIYVQNS DNEEEELRKN DVFFSFEEEN PITKPLQVDL LNACYTRQLI RISNLRITLG
     KWTTPILSPL SITLAQRKLL FAESWPKHLV NEIVTRENSV ILHPQVHLSL NAFSVRSLSA
     YGIFLSSNCR TILTGLSYYF HNETYSENEG FCAPPNERRL ASFFRSSFEE QPNFLNLNAK
     GSASFFSQSG KSKSVTSATL ETSTIIGNLV NSLNGTICPI FDRSSIDSSQ MLSIHIERKI
     VSGFGDIQYP ALIVMKADSL KFVLTSALIE WFKDVTMKLE KSWEAFEEES TTEKFSIKSQ
     SCVSAQKLDL QGSTSRNAKS INQSVSSQNK PGESTYVMVT EPEKISIAGP IIYLCPVNDH
     YSTDDSSAWF TSLSSSNRAK VVQISFPRIE ITGPSTHSLE SFQSQPCPPP IDEFPRIRLY
     SLEFEAKQME EEKKLMRRIL SNPESEAPES LNPSRLKWDC QASGIEISAR MSPSPLFQMG
     KVEFTLSFTI SLPKPTADPS SIDWDLVIKL SSDETTDSNS SPNLKDAIQF LKTISDIQSE
     IGILISKIGV TKHLIFPQAK GKEGVIPSAS SISTAPEVVP CESGAFSSSS MVSHATYTSS
     LHPLSMSERA SHRISLKLPE NENSRILVRG SVQLTLPSTT GQLYLNDDGI SAIRWEIEGF
     GVSTLISHST SFIHFRTKFE RICLLLQTRD RCYPLLSPKN WHLRPFQNVT PCPGSDYSVE
     SNVVASRPKP ITPQGGDGEN EIDITPSRLY QPTSIFTLSL IRCSAGVLRK VFAGKRFTHW
     LDRESEQFLQ RDKFMECKNS SPPFVNCIYF RVKPMDVVLC PQLVAHIRDA FGEGSDPDKV
     MSECGTKTPL AVVRAPLPGH CMPLVFAAAN EMRFFLPSPG LMNPKIDGAA QIDTIVLTVG
     ALRLHPFPTN SITSRPEPSG ITSTKPVYLK TTIGSPLEDR QFILHLDSLA CWAVKIVNSL
     NCSKIPHRFD YQPTLAGQYP AFEWNQAATR LSDVKDAIWV LPVLRSLNVT AIYAAPVCDN
     SLVSGQKRIL LDSALEVNIS HDIIITLCVS FLKSYLSHLS DALTSTSAVQ PSKIRQNSER
     PCQYVPRMLL TCGLMRCVIW ERRSTAENIW DFLVADLIQP HLMWSPEGLN AAINDLRVYL
     RTFSDEANSK FQRSVLWIPT LPKPSDREVS IVPSCLPLPY VEESSHCHAS DGVCFSTFGD
     EELFVVNLSR QNSKDDLFEA TARVQRNISL VLTPAMLMCL TTLSKPFQSS NVSTELIKDA
     DRSTFSIPAY AVKSLSEVSF SSRSISIGLI TPEDKAKFSV EVITLKGSST NRKDWRSLDS
     RLRVSNITVS LDHFQCIPSG AELYLKFSIE MSSVNPSIIS AQLEISRGTR LTLPLGEEIE
     RFTRALGCVN NCSATTNKKI RPFQFLPQRQ IFIDDLRQKS AYDFSVYVPT GPSGLGDTSR
     WVPLPFEIVF ADCDQFSQEA LAEERCATMT WTFPEPRQIM RLSVNPVPLV YENDYGKTGG
     IMLPARLQYW SEQIGEYGGF VTYATFELRE DTTVDVSLPE ISENQQTLKK AHRHGLVHRP
     SGNEKEDIFW GSKADLTTTD LPIVAATWRI IVSCVGQCSS ATNSTGPFPI FLSPYALAAC
     TYIDSVYIPE LTRPISIRFK LNDFCLSSLK KTKQTSLEIG CLTVSNLRGL LATSFQTDLM
     PLWSFSLDLA TVHVFDPHGA HLQLLGQAER IYGVSGDVSI SVGSCCLCCS STLVYALQSI
     LNEDSTEGWT IRNRTDEQIC VEQYFAGGET NEPSAEALKD VTRFIIDAGD YKCSWRPIVL
     PKADSRNRTI SLRVKTSTDW SVPISITWPP VHNTSTISYP IKWLSTGEEK ETSHTLFLLI
     PPRPSSGIPG EVIIQPSFNI ENNLPISISI TLPGVINKCI EPCSTHGICV PLDNFDFSLS
     ASYTNSTTKI AWNELASAKR KIILLPIGEN VSPILLKVDN PSGSIRSITL TPALNITSAF
     PMPLTLEVTT KSDVHFLILS SGNFSKHVDI PQKSLKSVMV SFQPGSHPTF NFRYPNLSPV
     FDSPLSLPLE TASNQIDVFI QPWLLLSNHS GINLQIFTAD SLEDINHPDD SGPDLNDGAS
     FIPATGERLL KLGIHYKGEV VWSPPILVHN SVFAPAQSLA PKDSSSDGTL VILTASGTKH
     QRGKRRSIGQ TPADAVVNLN RDQPLSSISI RLGGLICSLS VRLNISEQSL KGSGNGEIVT
     LRIEPLLQLK NRSNRALLCK PIAAPNIQIQ QSLYIASVDE LNGEVVALPS SVDEKFIPLL
     FWNFTHPDVV FKGVDSKGIL FAHLLVLRSR LGVFWSRSLQ LDEITSTDGV RMFESTGPLR
     RYYHVSLTGY DEDGNSNEYS LLLTLSNESG PGIWTLYLDN MSTSLSATLG CNLINTTNHS
     IEASIEFHDF HKFPVSNALP CAYPRGGKLT IIPQSGLDRL VGMQAFDEPP TSDFLHLEST
     ALSLHLNSDE VTVKLIDCDR KPLSLTFSET VIFIWRVVDQ AVPSSIQLVI FTEKNPPPHS
     IPPVERPLSL SIYIDTVLIF MIISGSLLKQ DDSRLRNFVR ISIRCIDGSF FRNGHLSVSE
     FSVTSSMIQV DNLAQLTSST FDFPVLLRSV LSHAVEGNST GSFSCSGQIR QIQPFSDLLL
     DKFDLRLPSI EAYLEDSVLY TLISWIDDLK SVRSQKVESA NTNDQFPAIL CLRDLHIHPV
     AIQLALKAKM GFHISCKTTQ FRLNKFARSE AVLQASTLVA QLSTHYISQV LIRAGIVLGS
     LELIGNPVSL VASFAEGVSD LVNFADSEKA VSKEHLDPLR GLARGLVSVV KHTTGGVCNS
     VTGMASSVAR NLHELSLDAE HIQRTTETRQ RHHPIGLGDG LALGLSEFGV SLLGGLAGIA
     HHPLFALVDS TPTMLSPMSP DTQDTISSSL TSTSIVSTAE ALAGGVGRGL VGLVAKPLAG
     VADLVAYTGT GFMHGMGTGW GITPSPSHMS CPILPPDAIQ LVDTSLLHDW SCTLMRRLDL
     PQFRDYLWSG LGTDTNHVVL TWLCLPYPGS LFAVEFKSAV QTIRAGVIPV NVADASVEEE
     WEDILAKDAS NSEIPSLLSR CRLSGGDKAV LKRVLQRSSR SEEITREVDG DAVTIESSPH
     LERYFVDYKL NTTISEKADY RINFLGYIGI ASQFPNLIMA AFNTFFQKKS STSNPTFRFM
     VVMGLELVIL ILTTIMVFVD TSNGCVGIHQ TLTFGLAAFL PMKYSNAVIM GTNICGVFVA
     SVNMLVKGLA EIWGESERSI IITRTCYFAV ATIYVVVCVL TYISLRRLEF VRFYLNLKGS
     DNVEEIDATQ EATTLVTKNT PEDVEDKSEE GPVATCSPRD FVEGQMLNDN TDKVEDDEGI
     SAWDTLRNCF AVCCFAGAEG HRLCEAYWRR YKETFRECWL QCLTVWMVFV CTLALFPSVQ
     STIKPSDPSY IIKESWFVDI TCFFFFNLFA LLGCVVSNWP GARFLWVPVL LRLIFFVPFF
     LLSNYRIDGR VADRRMPLWI TNDHIYVFGS IVFAFTSGYF SSLAMMYAPM RSPPERAGLA
     GLLASFFLIF GVFCGCNLTR LLMAFL
//