GenomeNet

Database: UniProt
Entry: A0A0R3SS49_HYMDI
LinkDB: A0A0R3SS49_HYMDI
Original site: A0A0R3SS49_HYMDI 
ID   A0A0R3SS49_HYMDI        Unreviewed;       869 AA.
AC   A0A0R3SS49;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   12-APR-2017, entry version 5.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Hymenolepis diminuta (Rat tapeworm).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX   NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000808001-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000808001-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:HDID_0000808001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   WBParaSite; HDID_0000808001-mRNA-1; HDID_0000808001-mRNA-1; HDID_0000808001.
DR   Proteomes; UP000046397; Genome Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046397};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046397};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    430    455       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    476    493       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    568    586       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    598    625       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    657    680       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    803    826       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED       94    121       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   869 AA;  99035 MW;  E3A88A3553D55839 CRC64;
     MGSIFRSEDM QLSQLILHTD SAYNCIAQLG ELGIVQLRDT TPDVNAFQRK FVDEVRRCDE
     MERKLRYIEG EIMKDNISVY EPDEIPEAPP PREMLELEAT LDKLDHELRE VTFNAEQLRK
     SYIELTELKM VLRMTQIMLE HNTLEVNTSL TGAEDVLVEV PDVRESHGYI ELLPSDDFDV
     GFRQSGGLSS TTYRSHHIDF IAGTILRDRS ASFERMLWRV SHGNVYLRYA DLEGIEDPIT
     GQMLDKCMFL IFFQGEQLRT RVEKMCEGYH ATIYACPDTQ DKRQAMLLDV TSRREDLQVV
     LNRTTEHRAR VLESAAERLR EWFYKVYKMK SVYHSLNLFN LDVTTKCMIG ECWSAVSDLD
     AVQMALRRGM ELSNSTLQPI LNRLHTTERP PTFHRSNKFT AAFQSMVDSY GVARYREVNP
     ALFSVVTFPF LFAVMFGDAG HGLIMFLGAL FLVLWEKKLI AKKIKSDMWD MFFGGRYIIL
     LMGLFSIYTG FIYNDIFSKA TNMFGSSWYP LFDNSTLDTP TDKQLNPTSH AENVTGMFVG
     YPYPFGIDPV WQVSHNLIVY TNSLKMKMSI IVGFIHMLFG IILAAFNYKM FKDPLSIYCN
     LIPEVIFMVS IFGYLVFAIF FKWIVFDSSD ASTAPSLLTT LIDMMKFNYD TTSQTPALYT
     GQVVVQRILF ILAIFSVNAI RAASYGGTRT TDDTEIEGAT TDYVPFRNES SPTFDRSSRT
     SESPVGGSGS SGGGHGGHGD SEEWNFTDIM VNQIIHTIEF CLGCISNTAS YLRLWALSLA
     HAQLSEVLWS MVMSKGLSMD GHIGGILLFF VFAFWAFLTV AILVLMEGLS AFLHALRLHW
     VEFQNKFYEG SGYPFEPFTF ANIEKVSME
//
DBGET integrated database retrieval system