ID A0A0R3WA19_TAEAS Unreviewed; 2647 AA.
AC A0A0R3WA19;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Spectrin beta chain {ECO:0000313|WBParaSite:TASK_0000734901-mRNA-1};
GN ORFNames=TASK_LOCUS7350 {ECO:0000313|EMBL:VDK38231.1};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000734901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000734901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK38231.1, ECO:0000313|Proteomes:UP000282613}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spectrin family.
CC {ECO:0000256|ARBA:ARBA00006826}.
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DR EMBL; UYRS01018605; VDK38231.1; -; Genomic_DNA.
DR STRING; 60517.A0A0R3WA19; -.
DR WBParaSite; TASK_0000734901-mRNA-1; TASK_0000734901-mRNA-1; TASK_0000734901.
DR Proteomes; UP000046400; Unplaced.
DR Proteomes; UP000282613; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR CDD; cd00176; SPEC; 6.
DR Gene3D; 1.20.58.60; -; 9.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR001605; PH_dom-spectrin-type.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF15410; PH_9; 1.
DR Pfam; PF00435; Spectrin; 4.
DR PRINTS; PR00683; SPECTRINPH.
DR SMART; SM00033; CH; 2.
DR SMART; SM00233; PH; 1.
DR SMART; SM00150; SPEC; 11.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 10.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Actin capping {ECO:0000256|ARBA:ARBA00022467};
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000282613};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 55..159
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 182..287
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 2482..2595
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 2294..2336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2348..2483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2597..2647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 899..933
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1345..1372
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1698..1725
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2365..2408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2440..2462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2597..2614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2615..2633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2647 AA; 303933 MW; 8796D7BF19518942 CRC64;
MDTQLARPLH ASNFFPQYDV PICTQYALGP YNSSTNGGKL YERTRIKTLA EERERIQKKT
FTKWSNTFLL NDQLMIEDLF TDLCDGRILL RLIERVSGYK LPTPTPGRMR IHCLENVEKS
LAFLDKLNVH LENIGAHDIV DGNNRIILGL IWTIILRFQV QNISVIEKVR HAGYEDLIGL
RRNSTEALLL WCKAKTQAYP NVSVTNFTTS WRDGLAFNAL IHKHRPDLID FASLSPDEPL
RNLQIAFTTA ERCLGIAKLL DPEDVVVEEP EEKSIITYLV SYYHYFAREK ANTVHARRIE
RVINLLKCFI NDVKDYEVSA DKLMRWIHES ILHMNEASLQ GNLESLQHQL VELNQFRNQE
KPPHFYEKGE LEVAFFVIRN KMLATGMRVY VPPKQLRISE VNRAWEVLEH CEYKLWLNLN
DELRRQEMLD QLFLKFEKKC TMRESWLLEN QQIVGQELVG STRYALQIAQ KRHEAFEADV
FAYEDRIKLI VEIANELRRC QYFQDHIVQS RSQHVTNQWK ILLETIKNRR LLIQQRIACR
ECDTEFDHLM KIAAELKDRI GKISPGTNFE QAQHALVQME ATDNEIKTLC TQVDNLLTKH
RGGYGEELEK EWFGVADQIM LLAEEKRREI ELVDLQWHLL PEVSRYKNYV LNRMRFIEAM
EFKLSYNAAN RIHRQVRYIE EDVTKEQSQV NLIEELFGGS IYNHQLHELA ALWRLFNEIL
SSLKSKAVFI GDVLFLNGEF DDAENWIAEK IKIVELEDSS VESSVHLNQK LLEEVEVYLH
VIEHINEKAM TLKESCKSFD TLPHDSTETF NAKVLMQSLI KVRNEIERIL VEKPESLLHS
YLALADKVKK KQASLIDALS IQLFTHNSNQ ARAWVADKSS LLARLKRADL NAIYEKGVSA
DLQEEFDFVE RRFEGIENQM SDMAEQVANL NRTASNIIDA ATIGNFPDAK AMLSQVTGTR
NQLNDAWNQL ADQVEDCRYR LNLDHAFLNL CQDCFYTNEW IKEKLAVLSR HNWTYIPSVS
HFSRLRIVLK SLKSDAKVIR AKVDNIGERI TDSYHVSDGL SNERGSWLFK EHDALSGKLS
GLDRQLDQCE SLMTLHGGHL QSAQSLGEFL QWVFFLKDKN SCISIPSNLE EIRASVCSQE
QDLQELLTAE GHLEELLAGY EKVYTLMDTE KPVKESRVNP EQVIEEYAET CDLVRKNIVN
LNQSIAIQDL LTELGGLEAA VYQQDAYLNQ KFQPESLEAV ENALKRHEAF VSSMVACRNR
FNALERKSRE TLTGDHSIEG RFFAKTNSLR QKLEDNEKRA YELERYLKEN FRLQELLNDF
ADIEDWMSEK LVTLNRVMLT SKRDVSNAYS QVKAVQEEIE ASRERAEGII EAGKQLIDSC
PRVSRVVSVS IDNMYVHWEA LLKELHKQML SLEESHRGKL ALSIFFEYLL NKTVQDLLRW
AEKLLSKVKA DIEDATLTTE GLTELQQRLD SHRRDCQSFE NYSEMADVIK EHTESLSQQH
PDRATDLAAV NTEVDKQLHA VNAALAQRED LLNLHITVTS HLLDLNSELL WVKDKLVQIR
QPYNDWTPQD RWSVGKHLLR VQQENRRLMN YIAEVENRGP RVKALCLRVK EAYLGTSEDA
AQRVGSFREV LGELEQAWYT VTHLLEVRRE ELRLAEAIHK FFFDVVNMEA WISERELYLQ
SICEPTNIEE ANRFLRRLNV LHETVKQWSN EVTKTERRAN ELCAQLSSGV QINGNCVIAP
PGAKSAVVNT ISRLVEDFER LESSVRDCRK DLVESISLHD LMQDIKDLEV KNFTLKSESS
YTTTVKTSEH SVCYRPLSFQ LWSSRVTLKT NSGIESRIPK HVANATEFFF ARSTGPKDWI
AERQKTAKDS DVGTDLEHTF NLKDRFDQFV KCTRREGENR VKTMLLRIDQ IIAKGHKNRS
EIALAKDGLN EDWADLLEMI TTRGQLLKSA LTLYRFFSDA QYLEKQIEEF YQYLPEEPTV
EMVTDQLTSV GGRSGGIASL LRRQAGVQQR LSHLNSSCAA LAATAVALLP TYSGEEEVRL
RLRRDCVLSA AQSLAATAEV RARQLEEAQH FHRFFSTAHS LISWFDEAKD KMSQPNGLSR
TIHGVERLIA EHRQLYAEMG IKIKQVEECL DVGRAILGIG THSTTDEAAR PATSRLHAVL
TAPQGEVRET CVTLATERIL IEALWRERWE RLGMLLDIRY YMRDAAAAES WLVSREVYLV
SVRRNIGETL AETLALLGAH YAFERACASA EERFAALKQL TKMEIHALEW KPEDASRHEK
QRRDNIRRAV HEFLPPSDSF TRLPPQPPQP VPSRGQSVAG VGTSKEPGLF EPNPMVTRPM
VTQSVRTSFP PPAPFERATG VTRTVPIPQK RTSRASLSAV AVPKSTLVHQ EQPPRPLSSS
STTNIFFPRR ARVTPPKNPS DEPATSTTPF EEAEEGRTLE TTSSTRFVYG SFPSTSANTP
PPETHAEVAE PETTLPTSME EMPRVEGPLI RKWESEAGGM RHSRGRGWTS VYVTLIDGRL
TFYRDRRTRR EHVGETFHGE APMDLSGAIA VPALDYTKRP FVFRLRLFTG AEYLFQAVSA
EVLQRWIDAI NDSASKLTRR ESRNTHERAH SLPPSSRHSR ASSTASGQVE GPQKRRHSSL
RRILKRT
//
