ID A0A0R3WDA7_TAEAS Unreviewed; 1083 AA.
AC A0A0R3WDA7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
OS Taenia asiatica (Asian tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Taenia.
OX NCBI_TaxID=60517 {ECO:0000313|Proteomes:UP000046400, ECO:0000313|WBParaSite:TASK_0000874101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TASK_0000874101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
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DR AlphaFoldDB; A0A0R3WDA7; -.
DR STRING; 60517.A0A0R3WDA7; -.
DR WBParaSite; TASK_0000874101-mRNA-1; TASK_0000874101-mRNA-1; TASK_0000874101.
DR Proteomes; UP000046400; Unplaced.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17752; BRCT_RFC1; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
FT DOMAIN 339..419
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 52..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1004..1083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1019
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1042
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1043..1073
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 117960 MW; 7FDD0CD66F4CC5B5 CRC64;
LTFEESLRKA EMKKKVEGVL KSRKTLHDFF SVPKGAAQSG KDSKKAISAA DYFASSSSHK
TPPQGKGPVA LVPETPLASQ GVGETDEGEI CLSASMVGKP LMPSPSALRK EKRRSVSKMK
DSSVSKDVPE VAQVPYDVRK EEKQSTGREE GSCASKDVSK TPSKRGSKDI QIYRMESGHK
VDDNSTPKTV PKTPQKKVFF ERPFLFLTAD IHLHNIAAVL EVLAPFGNAI MATSYEVSRH
LSFLQIVLIA STRQQVYVVE IQNQYGNFNT TRLSVTLQTS SGTNTPKKKL VPSPSTPTTK
KSPSTTTPKQ ASGGGRPYFW KFQNREGPQA LGSRPIPKNT STCFVGKTFV ITGVLECIER
EEAERLIGRG GGRVTQAVSK RTSYLVVGRD SGASKLNKAV SLGTPQLTEE AFFDLVDRGF
GKVDADEEDN DKCDTAFSLA PSSTILGTPL TPSPRKKMKK VKDESSQSVL LTDRPMIPSP
SLKKTATTEP VNQELWVEKY RPRSRKELVG QNGAASPANR LYAWLSSWQE NYATGNKAKS
YSSAPPWAAG GSSDSGAWAR AALLSGPPGV GKTSTALVVC AELNLVTIEM NASDTRSKRS
LQEEVAQALG MRSLTGTFVS PSAKTLALTS HVLIMDEVDG MAGNEDRGGM QELIGIIKTS
KVPVICLCND RQSPKIRSLA NYCLDLRFHR PRVEQIKAAV LSMVCREGVN VSPTALNEII
IASNHDLRQV INSVQMWCMN GGHHKTGVTE ADITANTAAA HKNLRLGPFE VIRKVFAPYI
DGEPVSFTEA MGLFFQDYSL GPLFVQENYL NVRPVAANGN AQETLDLLAR AAMDIAQGDI
VSRVMQSASS WSLLPTQAVF ASLRPGRLLR GSLPGGPGGI SSPAWFGRNS TQTKNARLLA
ELSQHMRIST HGGAADSRSL LLDYLHPLAV RLSAPLKEGD INSVLQCLDA YQLLREDMDN
LMDLTTWQDR PSPMKNIDAK VKSALTRTYN KTVHKVPYAT ELVGGGRKRR KRQGEASSEV
TLEEEGEGSQ FLEEESEESS VEEEEEIRKM AKVKTIPKSS AESSKEKPTK KPSGNGRRTK
RAN
//
