ID   A0A0R3WJK9_HYDTA        Unreviewed;      1130 AA.
AC   A0A0R3WJK9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=DNA mismatch repair protein {ECO:0000313|WBParaSite:TTAC_0000086101-mRNA-1};
GN   ORFNames=TTAC_LOCUS862 {ECO:0000313|EMBL:VDM17100.1};
OS   Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX   NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000086101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TTAC_0000086101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM17100.1, ECO:0000313|Proteomes:UP000274429}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UYWX01000114; VDM17100.1; -; Genomic_DNA.
DR   STRING; 6205.A0A0R3WJK9; -.
DR   WBParaSite; TTAC_0000086101-mRNA-1; TTAC_0000086101-mRNA-1; TTAC_0000086101.
DR   Proteomes; UP000046396; Unplaced.
DR   Proteomes; UP000274429; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 1.10.1420.10; -; 3.
DR   Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR   InterPro; IPR036678; MutS_con_dom_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR   Pfam; PF05188; MutS_II; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF05190; MutS_IV; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000274429}.
FT   DOMAIN          159..611
FT                   /note="DNA mismatch repair protein MutS core"
FT                   /evidence="ECO:0000259|SMART:SM00533"
FT   DOMAIN          620..766
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
FT   REGION          265..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          887..924
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1003..1057
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        894..923
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1003..1023
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1024..1038
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1039..1053
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1130 AA;  124583 MW;  E9387403AD0C63B3 CRC64;
     MAVIDLNQPG IEVSQFTDTS GYGSTLMKML VWMPTEVLLP QSALEQSSNM NRLVKLLQQS
     EFGCAIVGVG RHSFNNQEGL EYLKALCHPH YLPSIYAFQE KYYGLSAAAA LFNYLETTKR
     VYYAPKSLKV DFRCSTQATM LDATSAIRLG LVSRLGRARE SQTLFKAINH TCTLIGARRL
     RGCLLEPPND LTTITCRQES VTELISKPQI LLEIQTVLAK FPAIDSLLSM CVHLSEFPAP
     RTDLLTGTAA SACSVITSSS GAAFRQRPTS LSGDDAAEEE LLTPSSDVER DHRPKRLCTG
     TASASNISPL APTSNLALRR RLSEKDSSGA TSSLFSAVSI GNNAELRITK LIAIKHMLDL
     IQPLQDALKG TSSALLKTYR EPGINVLLDL TRRAYAEQVD DISQYVKGLA SEYTLPLRVG
     YNKARGFFIQ IPEQALCLPP APRSRCFEAK ATSNLVSEST NCSRSNGPQS TRFSIGTQLT
     TKHPNLPDVF IKVQVSRGLI NCTTAELVKL NERVKGSLNE VYLIADNLAC KLIHDLHPEM
     SLFYRLSEAI SGLDLLCSLA RIVVSAPPGH CFGKSQIITD RSDTCPALLV KPVFGDTLAI
     QEGRHMIKDR FSECLPVSNN TSGKTTYLTQ VALMQILAQI GAFVPAKFAA FRLTDKIFVR
     MGCRDDMSTK ASTFALEMRE VGHILRSATD NSLVMIDDLG LSTTDEDCFT LSYAICDALA
     KMRAFSFFTS SDASLSQLQF IHLNVEIYHF EVETRGAIQG GQRIYHSRRA DCSLDDSYKS
     TSFNDSSIMP GEYEGAPTVD GTECAKDGDT RTLYRFTYRL RKGVGKITHC VIDQIGLTAM
     DPDLISITKK YYNILMSGKT SKINSVTHSD VVNVSHSTTD PVSIAGVEQV RRSESATSKG
     DQEEETETVT HHITSEKNEE RVGKVGNQVS PSLYQSYNFS EGKERDAIPR ALVIRNGDPD
     PEIICKRSEA NCMLDGNNSW LLFLQVLEHT DLNVDVAENA PRLTTLTPPT QLPANQTSKS
     CEDSQNGKNR DEDFRQENVG EAATTSPGEV TSEERGVTSV DRMAYRLMQQ VQMLACVVRY
     IERASTSAPD GSTNQKNREE DVRAAQQDVL LHLAFLRDRY AAVLKHLKED
//