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Database: UniProt
Entry: A0A0R3WJP3_HYDTA
LinkDB: A0A0R3WJP3_HYDTA
Original site: A0A0R3WJP3_HYDTA 
ID   A0A0R3WJP3_HYDTA        Unreviewed;      5152 AA.
AC   A0A0R3WJP3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 2.
DT   07-JUN-2017, entry version 12.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:TTAC_0000090201-mRNA-1};
OS   Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Taeniidae; Hydatigera.
OX   NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000090201-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000090201-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:TTAC_0000090201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (APR-2016) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   WBParaSite; TTAC_0000090201-mRNA-1; TTAC_0000090201-mRNA-1; TTAC_0000090201.
DR   Proteomes; UP000046396; Genome Assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 5.
DR   Pfam; PF00622; SPRY; 2.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000046396};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000046396};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4431   4453       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4645   4663       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4726   4748       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4926   4949       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5033   5054       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      345    540       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4169   4204       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4206   4239       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4182   4193       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   5152 AA;  568972 MW;  0E10CF02048F74A1 CRC64;
     LVPLPHIAEN RRIFTFKDFN TTGLFFPCVS MTARASARFV LGGTHGKLKH GPPAGYAPII
     DALQPSQRLR LEPVFSFGRL DKSIFSGPLA SPLPSQDVFV PVPISTDKVG VSMKPFETFF
     TIKATCLLSQ ILLPNVVERI RDKLAENLHE LWSMRKIEQG WAFGEVLSDL LHPFKGVDAG
     NVDYNGRRLE KNCRQQSTLP FRIFQRRDEA RRRHPCLCAF DKLQQQERQY NVTMALENLK
     TIFALRYNIG YESLPEGTRM KTIKLSASYT QSNGYKPQPL DLSAIRLSSR LETLVDELAE
     NTHNIWAKDR IHQGWTYGST EDNTQKRSPH LVPYSEVNAT IKKMNRESAT DAVKTLLAYG
     YVIEPVSGES EQSTSAVSSL SPSRFSLTSN SRENPLDVLE EATMNYRAAS SKAVTRGKWY
     YEVELLTYGM VRVGWATKNA PAATTIGMSG SSYSFAPEQA RKYHRDGRPY GKRCEPGDVI
     GCMLNLNERS ITFSLNGEIM MDPLGQEIAF KDIKVNYGFV PAFTLGSGQQ VRINFGNVVQ
     TLKYFTICGL QEGYSPFAVN MSYPVPMWYS KVDASLFRDL KPNHSRLETK VSGAYPPVIN
     ILAKSPSPTG LHQMEYLRLN LGIRCKSQFT SRSLVDRRAH LDHLRKQLEP EDYRHHGMGM
     GGPANIDLMP QEIGAGGLEV RDRRGKRARL ANVFRKTRPR DVSPDVTGGY SGAGGVSLVS
     GSASTSGTVG GKKTDPATPS QTSAGPHEGS PGPSGEEFEL LLPEQSALDN AIADFMDEFA
     YTVLIPPGQN PCLVNVGWVG SCFKISKPAS ISGGNPFPVD PDFNVTQLAT SPAPSTKPTA
     EGDTTSVASE SSASEKTSTS GSGIEMDKLL NFAEVRQVAV CLLHDDLTLK SAVAERSSFL
     VNVGDLIQKI STPEDIGKRV SQGLAVTCWV DTASGTLGFR LNDRDTLIRF QVEPSTHLFA
     AVFVRPTARD CVQFELGRRS RYHLPLTAGM LRPPRRANMP MPHRLNVQAI ERVHWAPVPG
     EQSKIQSMKM SDQRGWSMLL ENSAPRLAIQ LPEANRCFSI LELEEMPDLL KFHAKTLALY
     RALCCHGNHN VAQKLTSHVD QYQFLYVIQS KYVHGSLRSE FVELLLAMHL DSPMKLKQVT
     GREFIVPLEK DDLDVSKSPA HVLKIVYDWD PDHIPAVKEH RSIRPKLITD PYLLIPGADG
     TGAGNFAIPS GSGEAQPEAV LTSAVAAAGA SGLLKLSDCP SFPLDLLKRQ TLDALIDMAN
     TGGHVRDPYG GNFEHALLPL LLILNHLLVM GSLDAADLAT VLGLLSPKLF PNTPSWRGAA
     VFSILMLLFS GETFFAMVTP ITGSLLKLPL PESVKMEVCH LFHHLCDLQL RHRIESIVNF
     ANTAVSEIQN DQMQRYLAIK VANLPSAVAA PRTREFRCPP NVQIRNLLHM PGPGGPSGLL
     DDASCAAASS DNDAISPLDL ADACDDLTGD GCSRNPCAEE IKDLMRLFHH RLMNHLGVVK
     PEIEDTWDYD GAIKLLQEAA AAGLQHIIPL SNADTAGTLN NTANSLTASA LADGARQNTD
     TNSSSLNSEK SQSELTELLN IPTLLLPEGV GDPESGASGP PTAVKAIWNL VSGSNGTGSG
     SVDSGSRTSR QLALGGPEES KQHGRKLHQL ILETVSEWAS SSIIENVELI RQMFYLLYRQ
     YGALDEASEL CENTTARDIM NNNVFFQHPD LIRVLAVHET VMQLMVHTLS KASLDSPSVA
     AAATAAAAAA STASELQHQQ QHQGSQSPHS TAEDALSLRR RQGSGGGAGL PALMEEGEEA
     TLSGSNLGRN ASVGPTEMVV QCCRFLCYFC RTSWQNQKAM FDHLSYMLEN SSMLLARPSL
     RGICPLDVAY SSLMDNNELA LALREKQLEK VAVYLSRCGV QSNAELLTKG YPDIGWDPVE
     GERFLDFLRF TVWVNGESVE ENANLVVRLL IRRPECLGPA LRGGTKSVSS RRQRLNSQSA
     GHSGVAGSSG GGGGGEAIDQ LAPPGSPDVS GGAGGGTGAV NSAGSTAGGV GDDTHSTTAS
     NANAASSSAG GGLLKGIKEG IVMSAQIKLV KMAMDAEAQG LNPEDEDMGW RTVLMDYEDC
     NLFAPLPYNF SNLPPEEDED YVDLGAAILT FYSVLVDLLG RCAPELDASK SESVRGRAIL
     QSLVSMQDLE GVLSLRFILP PPKLEMQINA EGLEQWVDKS PMPPGLLPEH KAAVVLFMER
     VYGLTDSGTF VRLLENAFLP DMRAVTLLDS AQRGVTASDM TLALNRYICG SVLPLLTRYA
     HFLAVNEVTA GLLESTLHTA YRLATCRSIT NNQRDVVSDF LVALVEHIQP FSMTSLIRKI
     AKNMRTVGRE SVVSLRVLTT FYQRFGSYYS SEGWTSEYSS GGGESGGGGG SSGTTTGGAS
     KSGGAQRVTV AGSGAMRDLS DTAFVRATAA GMTTTATEEE KNLTAELFSL IFNNLSCRRY
     DAELYVYALP CLTAIGCALP PDYCSSHWDA QSRIGDDTVG LDAAGNCLDY ASHICPITVS
     AHPGGPDSAA DLRGSNQQHE SFRPTPLVTS SIRSDFLHFF EFPPEIKSGK VNSPPCGFMP
     SDRYYADTSY DVGWVHLQIK LPAALSILVD QFAKHCHDSW AQELVDQGYV YGLTLDEARR
     THPNIRSYHS LSQRDQMRYI QPVTETLRAM LALGWTIDPS GVCHEDDGTG LGLRRRQFIH
     SQTESPQGYI PAPKDLHGVN VTRELIDLAE RLADNAHQIW AKQKMEELEE IGGGVHQLLV
     PYDILTDRER KRYRRLTHEL IRYLQYWGYR LSCKPTNQQV DTTKAGTAAT PANAPSNAIK
     QYAGERGEGH PSSRFAYGLL SKLLDYVEGA MSTVREDKPS RMFSRHQNLT QTSEDMKLLV
     KVVLPLLERY FYTRKSYFID PYSGASIEEK KMATMLFTKL FTLLRLKTRC FGADVNVTVS
     CLKCLIECLD IKAIVKISYA EDFVRVRLMP FFSFCADDLN LIIRNLNSGR YSHIKGTIRR
     GACSIDYLHM ILLPTLKTMF EHISKTGVGE DLLLGHLQVT CYRILNALYV LGTTGRKHSN
     RPELMEELNR HRPMLGECLA ALTTCFPVAF LEPELSAHNP RSIAYNTEEA DYSFEARDLL
     QKISKTLPSL HNIIDDIVHL AEAGSSGTQE PHLIEVTLPM LCSYLPVWWR KNLAQRQYAR
     RRPGSKAASF FPDNEEFLAA LDAEGEGLLE LGNTGGGGGD SGDGGGDNGD DDDDEEKGWG
     AATGPITTVT ADLMNRVLGS VLQLIQNNID NSNAPWMTRI ATRTQPIVGN ATVDMLGKYF
     LPVSERLLDQ AFEVQSWERR LGNETDKEGD LTAACELLVR NMFALYPLLI TFVDRYRTEW
     LKQPTVETDR LFSAVANLFL IWNGSPNFKR EEETFVGIHE LDTLALIMPT AERGTLSTDV
     ASRPLSHHHI KSGKGPKKGF TSLMVASIKR LLPIGLCVLG GRHQELVQRA KRMFLKHEVE
     VDIIEYLRYA LDKDDNSETK TYRWQKLLYR KIDRMIALTG CHDALGESTK EEIINRIMTL
     AKVMHALYLV SHVVPTILNR GAWKKLVSTQ RKRAVMACFR MQPFYALPRH RAINHFLMAY
     HDGWLSYEQS LGVQLIEEIT RASPEEKTLS GANAPVPTPI AGMAPSGHSG DTGSGSTDAS
     SPNSGTGGGG GGDNEGMSIV ARAIIETSMY SDSSDEDNIS LSGGGGSDGS GAGGASGSGA
     IVASSAATNN EQAEDSSAPT EGGEHSVFAT DYCATPDPLR QLLTALCRTA MDQAPDDPLY
     LAFARIMAKV CTSLVLFPSH SHMRNSKDED DEIGGGNGGS GGDDNSAEEE EEEGPTSQEQ
     EEQKQRLLFE QNRLSDRGAA EMVLLELAAS KGEATPVATA SVELGIAILL EGNVSVQNRM
     LAYLAEKRLT GFFTSLAGLM QNCSVLDLDT FERCRKAEGL AVGLSDMEGI TNLYDADFTC
     KIFRLLQLMC EGHNSGNHRS GSWIPIAITR DLSLFCSTAF QDYLRTQSSN TTSVNLIIST
     VDYLLRLQES IMDFYWHFSN KPVIDESGRT NFIKAIKIGK QLFRTLTEYI QGPCQGNQHA
     LANSRLWDAI SGFFYLFAHM QDKLSKDPEQ LDLLHEFLNL QTEMMIMLLS MLEGNVVNGS
     IGRQMVDTLA ESSANVELTL TFFDIFLRMK EITNSDAFLA FDVNKDGWIS HREFRTALEQ
     QKSLNEEEIT YIMGCVDANL DGKIDFQEFT ERFYNPAREI GFNVALLLTN LSEHIPGDIR
     LERLLQKAKG MLEMFDPLLG RIEITNKEGR IERVYFEVRQ ENIDQWEKPQ IKESKRTFLH
     SVVGESGDKE KLECFVNFAE DTIFEMQHAQ GISGDDENLQ ISRVIKQSLF KLSPVSSSAI
     PLTTMTSVVA VRNLLEATRL SSVFAFLGTL ISFLSPHHLW KCWCSLRQMS FVDVITDILG
     LIIGLMIGAV RLIKGVLTIM GRFVVAMTSD PTDKTSEIPV SPPLPPTQST SSTIPLNVKR
     NQTAMLFNTM RTGGGKLEVT LNEDDAKPPD LGTANKEEKK PTDLANILQE KECWLLSEEE
     QLLLERVDSS KVEAFTGTTV QKPPPPTNTR PEPTPPNKKA QNIRPSPQTL DRETPEEPTV
     VEQKPIPTST FLISIFARNF YRFKLGALIL AFMINFLLLF YRIERRGVGG EGGGEEETFG
     ASFVTTITDT VSNIADSLQD TEVDVGMEGE EEWITLAESA SYLGPLLKIL AIAHSILSMS
     MLVAYYFLKV PLVIFKREKE ISRMLEFEGI WIAEQPSDER LRAQWDKLVL STPSFPHMYW
     DKFVKKKVLK KYREQYDQQQ IKRLLGMKDG GTNGGSSGIT AGGRPEEVST TWFYPTWLQE
     MDLQYLLWKW GVIFTDNSFL YLVVYFIVSL LGNANYFFFS CHLLDVAISF KTLATIVQSV
     THNGKQLVLT VMLTSIVIYL YTVIAFNFFR KFYTKEEDGE KEYKCNDMLT VSDFTIISLH
     ETNDIDAFSP LALQCFVFHL HTGLRAGGGI GDEIEPPDGD AHEALRILFD MSFFFVVIII
     LLAIIQGLII DAFGDLRDQL EQVREDLESK CFICGIGKEY FDATPHGFDR HVEREHNFAN
     YMYFLMHIIN KPDTEFTGQE TYVWELYQQR CLDFFPIGNC FRKQYEEELQ AK
//
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