ID A0A0R3X0L0_HYDTA Unreviewed; 559 AA.
AC A0A0R3X0L0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=FERM domain-containing protein {ECO:0000313|WBParaSite:TTAC_0000667701-mRNA-1};
GN ORFNames=TTAC_LOCUS6662 {ECO:0000313|EMBL:VDM30900.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000667701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000667701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM30900.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; UYWX01020313; VDM30900.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3X0L0; -.
DR STRING; 6205.A0A0R3X0L0; -.
DR WBParaSite; TTAC_0000667701-mRNA-1; TTAC_0000667701-mRNA-1; TTAC_0000667701.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13194; FERM_C_ERM; 1.
DR CDD; cd17097; FERM_F1_ERM_like; 1.
DR Gene3D; 1.20.5.450; -; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 6.10.360.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR011174; ERM.
DR InterPro; IPR011259; ERM_C_dom.
DR InterPro; IPR041789; ERM_FERM_C.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR008954; Moesin_tail_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23281; MERLIN/MOESIN/EZRIN/RADIXIN; 1.
DR PANTHER; PTHR23281:SF18; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF00769; ERM_C; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PIRSF; PIRSF002305; ERM; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF48678; Moesin tail domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000274429}.
FT DOMAIN 8..297
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 429..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 65263 MW; 67C21080FD251614 CRC64;
MLKRSKNKTI KVKVTTAESQ LEFEMQKGAL GQDLFDQVVR TIGLREVWYF GIQYIDKDGT
PTFLRLDKKI LSNDFAPGSE CDFKFMVKFY PENVEEELIQ TCTITHFYLQ VKSDIMSGKI
YCPTDTAVLL ASYACVAKYG PYDPHSCPKT LPIDRLIPGK DQYEQTDEQW FDRIITYYKD
HHDMSRDDAM VQYLQIAQDL EMYGVETFNI KNKKGTSLVL GVDALGLSIY EPDNLLDPKI
GFPWSEIRNL SFHDKKFIIK PADKTAKEFY FLVEKSKINK RILALCTGNH ELYMRRRKSD
SIEVQQMKIQ AKEERELKEA EKQRLKEERL QRMENEQKLQ ELRTQMLQKE SDLADMKLKA
SAYESKIAEL ESLLDQERHA RESLQRSQDK LAEMNRKLKE ETEASAEERN RLIAERDKVQ
REVEAQKVAM ATKEAEKAQA EAELRRMRER HDAKRKSDVN GSGDTASQDD ESEAKELEVI
PNAKRTEESR VTVVSKNESL QTKLANLKLE LNSTRDQSKM RDIDRRHEYN VREGNDKYKT
LRNIRKGNTM CRVEQFESM
//
