ID A0A0R3X6P9_HYDTA Unreviewed; 868 AA.
AC A0A0R3X6P9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN ORFNames=TTAC_LOCUS9177 {ECO:0000313|EMBL:VDM33916.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000919201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000919201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM33916.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; UYWX01020703; VDM33916.1; -; Genomic_DNA.
DR STRING; 6205.A0A0R3X6P9; -.
DR WBParaSite; TTAC_0000919201-mRNA-1; TTAC_0000919201-mRNA-1; TTAC_0000919201.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd16266; IF2_aeIF5B_IV; 1.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF11987; IF-2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000274429}.
FT DOMAIN 277..495
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 98615 MW; 3A8A62A596E1023C CRC64;
MADSVSTNTK KAVEDVTKTT ATKKNKKKPV KKDVKPTKEE IKKEKVSRKL NAIKEQIVRQ
REEEERLRKE AEEEERRFRE EMLKLEEQRR LEAEKRERKK QKEKERKQRL KDEGKLLTDK
EKENRRKVLE LAHARGLDLG ATKIDLKNRT YSRKKKRPQG QVEEPVLSQP VVEAEVKVEP
LEETIDGVID WEDLAADLVT SDNSECENLS LLSEGVLHGG VESSPSPPML ELDQSEVYKL
SESQLTEEEK RNLIEQVKLR LQRERAQDEE SVSERALRSG VICVLGHVDT GKTKILDKLR
NTNVQDREAG GITQQIGATN VPRENIIRSI QMCKYFTPND LKMPGLLIID TPGHESFTNL
RVRGSSLCDF AILVVDIMHG IEEQTKESIR ILLSRKTPFV VALNKIDRLY QWRSYPSLPV
EEALANQNEV TINDFNQRFK EVVQHFALME LNVELFYKNL NPNEFISMVP TSAHSGDGMG
DLLAFMCKEM QRRLYKRLTF SEELKASVME VKETVGLGTS LDVIVVNGRI REGDTIVLAG
QEGPIVTTVR SILMPAPMSE LRVKGSYEHL KEVVGAQGVR LIARDLEKAL AGLPLYVARD
LAEELYFKDE VSCGLKGALK AIAVSPVGVY VVASTLGSLE SLLTYLKSVN IPYSGISIGT
VHKKDVMKAS IMVERDRKWA VILAFDVKID KDAQKMANEV GVQIFTANII YHLQLRMEEY
VEALMKENRR KHANQAVFPV KLRILPDMVF NKRAPIVIGV HVEAGLLREG TPICVPSRDN
ALLGRVFSIE FNHKAIQEAR TGQEVCIRID PVEGEAPKLY GRHFDHTDLL ISKVSRDSID
VVKDFYRNDL NKEDWKLMAE LKEMLSII
//
