ID A0A0S1XZS0_9BORD Unreviewed; 489 AA.
AC A0A0S1XZS0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=NAD-dependent succinate-semialdehyde dehydrogenase {ECO:0000313|EMBL:ALM83275.1};
DE EC=1.2.1.16 {ECO:0000313|EMBL:ALM83275.1};
GN Name=gabD {ECO:0000313|EMBL:ALM83275.1};
GN ORFNames=ASB57_10120 {ECO:0000313|EMBL:ALM83275.1};
OS Bordetella sp. N.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=1746199 {ECO:0000313|EMBL:ALM83275.1, ECO:0000313|Proteomes:UP000064621};
RN [1] {ECO:0000313|EMBL:ALM83275.1, ECO:0000313|Proteomes:UP000064621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N {ECO:0000313|EMBL:ALM83275.1,
RC ECO:0000313|Proteomes:UP000064621};
RA Hou L.;
RT "Draft genome of Bordetella sp. N.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP013111; ALM83275.1; -; Genomic_DNA.
DR RefSeq; WP_057652121.1; NZ_CP013111.1.
DR AlphaFoldDB; A0A0S1XZS0; -.
DR STRING; 1746199.ASB57_10120; -.
DR OrthoDB; 6187633at2; -.
DR Proteomes; UP000064621; Chromosome.
DR GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010102; Succ_semiAld_DH.
DR NCBIfam; TIGR01780; SSADH; 1.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000064621}.
FT DOMAIN 26..485
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 489 AA; 52074 MW; B8D06592C15762B2 CRC64;
MSANLSKIEL ERPDLLRDLC LIDGEWIGAD SGRTLAVTDP ATGAQVGSVP FMGRAETERA
IAAAAAALPA WRARTARDRA AVLRRWNDLI LQHQRDLGML MTREQGKPLP EAQGEVAYAA
SFVEWFAEEA KRVDGEVLQG QRVGQHIVVL KQPIGVCAAI TPWNFPAAMI TRKVGPALAA
GCTMVVKPAE LTPLTALALG VLAIEAGIPA GVLQFVTGDA AAIGQALCES DVVRKLSFTG
STNVGRILMS QCAPTIKKLS LELGGNAPLI VFDDADVERA VEGIIASKFR NAGQTCVCAN
RIYVQAGIYD RIVERLVAAV GAMRVGNGLE AGVTQGPLIN DKAVAKVRQH IDDAVAQGAK
VAVGGTDHPL GGTFFTPTVL TGVTQGMRVA QEETFGPMAP LFRFETEEEA VALANDTEFG
LAAYIFTEDR RRIWRVSESL ETGMVGVNTG LISNEVAPFG GVKQSGLGRE GSRHGIEEYL
EPKYVCMQD
//
