ID A0A0S3EW72_9SPHN Unreviewed; 312 AA.
AC A0A0S3EW72;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=3-methyl-2-oxobutanoate hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00012618};
DE EC=2.1.2.11 {ECO:0000256|ARBA:ARBA00012618};
GN ORFNames=ATN00_04585 {ECO:0000313|EMBL:ALR19692.1};
OS Sphingobium baderi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1332080 {ECO:0000313|EMBL:ALR19692.1, ECO:0000313|Proteomes:UP000056968};
RN [1] {ECO:0000313|EMBL:ALR19692.1, ECO:0000313|Proteomes:UP000056968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DE-13 {ECO:0000313|EMBL:ALR19692.1,
RC ECO:0000313|Proteomes:UP000056968};
RA Cheng M., Meng Q., Yang Y., Chu C., Yan X., He J., Li S.;
RT "A Two-component Flavoprotein Monooxygenase System MeaXY Responsible for
RT para-Hydroxylation of 2-Methyl-6-ethylaniline and 2,6-Diethylaniline in
RT Sphingobium baderi DE-13.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodecamer; pentamer of dimers.
CC {ECO:0000256|ARBA:ARBA00011424}.
CC -!- SIMILARITY: Belongs to the PanB family.
CC {ECO:0000256|ARBA:ARBA00008676}.
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DR EMBL; CP013264; ALR19692.1; -; Genomic_DNA.
DR RefSeq; WP_062062673.1; NZ_CP013264.1.
DR AlphaFoldDB; A0A0S3EW72; -.
DR STRING; 1332080.ATN00_04585; -.
DR KEGG; sbd:ATN00_04585; -.
DR OrthoDB; 7592909at2; -.
DR Proteomes; UP000056968; Chromosome.
DR GO; GO:0003864; F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0015940; P:pantothenate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR003700; Pantoate_hydroxy_MeTrfase.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR20881; 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR20881:SF0; 3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE; 1.
DR Pfam; PF02548; Pantoate_transf; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE 3: Inferred from homology;
KW Pantothenate biosynthesis {ECO:0000256|ARBA:ARBA00022655};
KW Reference proteome {ECO:0000313|Proteomes:UP000056968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 312 AA; 33793 MW; 5DA9D3AA70B10B42 CRC64;
MLMSELVAPA HGQRGDSRRP IKLNLYRDYE VDAVAKAMAD SPVLQMGIRL DCLMVSDSYL
MTHLGRASTR LAKGEQALFL EIMAGLVKEV AHRAKQLFPY EAPYIVGDMP DGSVVNGEVA
VRSADRMRRA GADVIKLEVH SEAVIAIIER LTREGFRVMA HLGYTPQGGD GGRVGGSLDG
AYALFASARQ VRDAGVESIV LEKVDEFVHR ALVDRPEALP SYAIFSGKSE NGGQSLNIWD
SVFKPGFRAR YFPPTARETV DAFPMAYSAT TIAKHIGTLL SLTAAGEFPL SPPTLLSIDD
VVALASSDPW AD
//
