ID A0A0S4KQ27_9BACT Unreviewed; 574 AA.
AC A0A0S4KQ27;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:CUQ65278.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:CUQ65278.1};
GN Name=ftsI {ECO:0000313|EMBL:CUQ65278.1};
GN ORFNames=NITINOP_0302 {ECO:0000313|EMBL:CUQ65278.1};
OS Candidatus Nitrospira inopinata.
OC Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC Nitrospira.
OX NCBI_TaxID=1715989 {ECO:0000313|EMBL:CUQ65278.1, ECO:0000313|Proteomes:UP000066284};
RN [1] {ECO:0000313|Proteomes:UP000066284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Daims H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN885086; CUQ65278.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S4KQ27; -.
DR STRING; 1715989.NITINOP_0302; -.
DR KEGG; nio:NITINOP_0302; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000066284; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:CUQ65278.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000066284};
KW Transferase {ECO:0000313|EMBL:CUQ65278.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 54..197
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 243..549
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 574 AA; 62275 MW; BDCF46A908CF35B0 CRC64;
MAAPLSRGRR FFTILLLLSG FGVVLSRLVT LQVLQAAELT AKADRQHQTT VSVEGVRGAI
VDRHGKVLAM NLEVPSVYGV PTVLDSPART ARELAPLLHV RSEDLERKLR QPRGFVWLAR
KVDPDRRHLV ERVSSMEGVG VKMEGRRFYP KGPLLSHVLG FAGMDGEGLE GIERRYEKEL
RGEKRAIVLQ KDARGRAVFP KGLSEEPAPA PGHQLVLTID EVIQYIVEKE LEEAVARSRA
KSGTAIVLDP GSGALLALAV SPRFNPNAIA GLEPDRWRNR AVADAYEPGS TMKAILAAAA
IEEGVMTPTT LVYGEQGRLA VSNTVIHDHE KLGWMSFAQV VQKSSNVGAA KVGMALGEER
LYRYFRAFGF GERTEIDLPG ETAGLLKNPK EWGKRTAASV SMGQEIGVTP IQMVSAMAAI
ANGGILMKPY VVSEIRDAHG LVIKRVLPSA KRRVISPETA RTVTSILEGV VTDGTGGKAA
IEGFRVAGKT GTAQKIDRRT RTYSTTKFVS SFAGYVPAEN PKLAMIVVID EPNGEAWGGT
VAAPVFRRVG EQVLKYWGIS SNEPVRLAMA TARR
//
