ID   A0A0S4KYR9_9BACT        Unreviewed;       478 AA.
AC   A0A0S4KYR9;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Glutamate synthase [NADPH] small chain {ECO:0000313|EMBL:CUQ68350.1};
DE            EC=1.4.1.13 {ECO:0000313|EMBL:CUQ68350.1};
GN   Name=gltD {ECO:0000313|EMBL:CUQ68350.1};
GN   ORFNames=NITINOP_3379 {ECO:0000313|EMBL:CUQ68350.1};
OS   Candidatus Nitrospira inopinata.
OC   Bacteria; Nitrospirota; Nitrospiria; Nitrospirales; Nitrospiraceae;
OC   Nitrospira.
OX   NCBI_TaxID=1715989 {ECO:0000313|EMBL:CUQ68350.1, ECO:0000313|Proteomes:UP000066284};
RN   [1] {ECO:0000313|Proteomes:UP000066284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Daims H.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR   EMBL; LN885086; CUQ68350.1; -; Genomic_DNA.
DR   RefSeq; WP_062487582.1; NZ_LN885086.1.
DR   AlphaFoldDB; A0A0S4KYR9; -.
DR   STRING; 1715989.NITINOP_3379; -.
DR   KEGG; nio:NITINOP_3379; -.
DR   OrthoDB; 9803192at2; -.
DR   Proteomes; UP000066284; Chromosome 1.
DR   GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR006005; Glut_synth_ssu1.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CUQ68350.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000066284}.
FT   DOMAIN          23..129
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          147..456
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   478 AA;  52752 MW;  076FBB64679440FD CRC64;
     MGDPKGFIKF AREGPKRRPV ELRVKDWKEL YEPISDEKLR VQGARCMDCG VPFCQSTNGC
     PVVNLIPEWN DLIYRGRWLS ALKALHATNN FPEFTGRLCP APCESACVLG INEDPVSIRV
     IEWNIIEHGF SEGLVEPILP VSKTGKRVAI VGSGPAGLAA AQQLCRAGHD VTVFEKADRI
     GGLLRYGIPD FKMEKWVIDR RLDQMRAEGV TFETNVAVGK DLSGDELLKR FDAVGLTLGA
     EQPRDLSVPG RELNGIHFAM DYLTQQNKRN AGDSITDEPI TAKDKRVVII GGGDTGSDCL
     GTAHRQGCRE VHQFELLPEP PPQRAESTPW PLWPMQLRTS HAHEEGCDRQ WSVSTTKFSG
     RNGHVTKLHA HRVAYGNGKF TPIPDTDFEM DVDLVLLAMG FTGPVKQGLL DSLGVKYDQR
     GTVQVDENFM TNLDGVFAGG DTRRGASLIV WAIAEGRKMA AGIDRYLRAG KSAKRARL
//