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Database: UniProt
Entry: A0A0S4T5X6_HYMMI
LinkDB: A0A0S4T5X6_HYMMI
Original site: A0A0S4T5X6_HYMMI 
ID   A0A0S4T5X6_HYMMI        Unreviewed;      2190 AA.
AC   A0A0S4T5X6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   22-NOV-2017, entry version 9.
DE   SubName: Full=Hypothetical transcript {ECO:0000313|EMBL:CUU97612.1};
OS   Hymenolepis microstoma (Rodent tapeworm) (Rodentolepis microstoma).
OC   Eukaryota; Metazoa; Platyhelminthes; Cestoda; Eucestoda;
OC   Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX   NCBI_TaxID=85433 {ECO:0000313|EMBL:CUU97612.1, ECO:0000313|Proteomes:UP000017242};
RN   [1] {ECO:0000313|EMBL:CUU97612.1, ECO:0000313|Proteomes:UP000017242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nottingham {ECO:0000313|Proteomes:UP000017242};
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A.,
RA   Sanchez-Flores A., Brooks K.L., Tracey A., Bobes R.J., Fragoso G.,
RA   Sciutto E., Aslett M., Beasley H., Bennett H.M., Cai J., Camicia F.,
RA   Clark R., Cucher M., De Silva N., Day T.A., Deplazes P., Estrada K.,
RA   Fernandez C., Holland P.W., Hou J., Hu S., Huckvale T., Hung S.S.,
RA   Kamenetzky L., Keane J.A., Kiss F., Koziol U., Lambert O., Liu K.,
RA   Luo X., Luo Y., Macchiaroli N., Nichol S., Paps J., Parkinson J.,
RA   Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M., Salinas G.,
RA   Wasmuth J.D., Zamanian M., Zheng Y., Taenia solium Genome Consortium,
RA   Cai X., Olson P.D., Laclette J.P., Brehm K., Berriman M.;
RT   "The genomes of four tapeworm species reveal adaptations to
RT   parasitism.";
RL   Nature 496:57-63(2013).
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DR   EMBL; LN902919; CUU97612.1; -; Genomic_DNA.
DR   Proteomes; UP000017242; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 3.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000017242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017242};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       59    113       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      120    166       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      175    242       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      248    307       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      325    383       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN     1044   1245       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   2190 AA;  240250 MW;  15B0FD0E2BF6CC37 CRC64;
     MGAEGFGNRM CSLESIAKEV PPANMPPCIF ILEQALSARA LQEMLSSRNE LSDSRTSGHR
     TLLYGHAVRL KHRNSSMYLA CLSTSSSEDK LAFDVGLERE ANTEACWWTI HPASKQRSVG
     EKVRIGDDLI LVSVSSERYL HVYGDSFSTS GVIASFQQTL WTVIPVSSGV VRQKSLHMAF
     GGDVIRLFHG DECLTIQSAG DTEEGHFISN EITSSSDYHQ SVMYQLGSVS GHASSLWQIE
     HTKIKWCAGF FSWEDAVRLR HVTTGRYLGI TQVNAGGAPT APGQIDVVLL SPEESNDAST
     VFYIKQTKDD KKKVDIDREH EGMGEPNVCL GETLIYLQHA ALGWWLSYES YETKKRGVGK
     VEEKKAVLLA EGHMDDVFSL VRAQEEESLS AAAIRRSTAV FSAFNRGLDA LASTEGLGGA
     SGGPVSAPPV IIGSGEHGLL NLEEVNQCLE DLIEFFAQPG THEEHEAKQS KLAALANRQD
     LFQEEGMISL VLETIDKFTG AFRSRREFAL AVGEERGSRF SDLGNYLYLL LAALIRGNRE
     NCAQFAAPAR LDWLFNRLEL QQSFAEGVLD ALHCVLTDSD EALNVITAQH IHTLIGLLDK
     QGRDPRVLEV LYSICMGRQG GAVRLNQDLI YESLLPERDL LLQTKLVAQS GSMRPNIFVG
     IKPGGSMYTK WYFEVFIDAL ENISHQPAGI RIGWGNTDGY TPHPVGGPGW GGISLGDDFY
     SFAFDGQNLW TGGKAKQALF PPGTGGKLTP RRPGAATSAA PANGSTNLKR GDVIGCLLDL
     TGPVIQFNLN GNLVKGYFQD FNTTGLFFPC VSMTARASAR FVLGGTQGKL KHGPPAGYAP
     IIDALQPSQR LRLEPVFSFG RLDKSIFSGP LASPLPSQDV FVPVPINTDK IHLPNVVERI
     RDKLAENLHE LWSIRKIEQG WVYGERRDEA RRRHPCLCAF DKLHQQERLY NVTMALENLK
     TIFALRYNIG YESLPEGTRM KTVKLGPAFT QSNGYKPQPL DLSAIRLSSR LETLVDELAE
     NTHNIWAKDR ISQGWTYGST EDNAQKRSPH LVPYCEVNSS IKKLNRESAT DAVKTLLAYG
     YVIEPVSGES EQTRENPLDV LEEATMNYRA ASSKAVIRGK WYYEVEILTY GMVRIGWATK
     NAPAATTIGM SGSSYSFAPE QARKYHRDGR PYGKRCEPGD VIGCMLNLNE RSIMFSLNGE
     VMMDPLGQEI AFKDIKPQDV AKGFVPAFTL GSGQQVRINF GNAVQTLKYF TICGLQEGYS
     PFAVNMSHPV PMWYSKVDAS LFKDLKPNHS RLETKISGAY PPVINILAKS PSPTGLHQME
     YLRLSLGIQC KPQFTTRPLI DRRAHLDHLR KQFEPEDYCH HGMGIGGTNI DLMAQDISGG
     GLEVRDRRGK RARLANVFKK TRPREVSSSE VAGSFSGAGG VSLVSGTGST GPGGKKGDAA
     SSSQTSGGAH EGSPGPVGEE FELLLPEQSA LDNAIAEFMD EFAYTVLIPP GQNPCLVNVG
     WVGSCFKISK PASISGGNPF PVDPDFNVTQ LATIGTTPNT PTNKRLEGEV ASLNSEISES
     EKTSNVDSPT VAMEKLLNFA EVRQVAVCLL HDDLTLKSAV AERSSFLVNV GDLIQKISTP
     DDIGKRVSQG LAVTCWVDTA SGTLGFRLND RDTLIRYQVE PSTHLFAAVF VRPTARDCVQ
     FELGRRSRYH LPLTAGMLRP PRRANMPLPH RLNVQAIERV HWAPVPGEQS KIQSMKMSDQ
     RGWSMLLENS APCLVIQLPE ANRCFSILEL EDMPDLLKFH AKTLALYRAL CCHGNHNVAQ
     KLTSHVDQNQ LLFIIQSKYV DGSLRSEFVN LLLAMHLESH MKLKEVTGRE FIVPLDKDEV
     ESIKSPAHIL KIVYDWYPDH IPSVKEHRSI RPRLLTDPHL LMLNQPSSER IKLISASPGA
     DGTGGGNFTI PPGGADSQPD AALSAALAAA GPGGLLKLSD CPPFPLDLLK RRTLDALIDT
     ANMGGHVRDP FGGNFEHALL PLLLILNHLL VMGCLDEADL ATVLGLLSPK LFPNTPSWRV
     TPISGSLLEL PLPESVKMEV CNLFHHLCDL QLRHRIESIV NFANTAVSEI QMDQMQRYMA
     IKSANLPSAV AAPRTREFRC PPHVQIRNLL YMPGPGGPSG LLEEVGSSTE AEALSALELV
     DGADALVIDG SSKNPCAEDI KASQFTKLRT
//
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