ID   A0A0S6W115_9BACT        Unreviewed;       951 AA.
AC   A0A0S6W115;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0008006|Google:ProtNLM};
GN   ORFNames=U14_04729 {ECO:0000313|EMBL:GAK53464.1};
OS   Candidatus Moduliflexus flocculans.
OC   Bacteria; Candidatus Moduliflexota; Candidatus Moduliflexia;
OC   Candidatus Moduliflexales; Candidatus Moduliflexaceae.
OX   NCBI_TaxID=1499966 {ECO:0000313|EMBL:GAK53464.1};
RN   [1] {ECO:0000313|EMBL:GAK53464.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sekiguchi Y., Ohashi A., Parks D.H., Yamauchi T., Tyson G.W.,
RA   Hugenholtz P.;
RT   "First genomic representation of candidate bacterial phylum KSB3 points to
RT   enhanced environmental sensing as a trigger of wastewater bulking.";
RL   PeerJ 3:e740-e740(2015).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; DF820459; GAK53464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0S6W115; -.
DR   STRING; 1499966.U14_04729; -.
DR   HOGENOM; CLU_000445_107_19_0; -.
DR   Proteomes; UP000030700; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030700};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        570..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          597..649
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          654..869
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          663..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          913..951
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          840..878
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        925..951
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   951 AA;  103414 MW;  0E81A8AC3C5AC4A9 CRC64;
     MVALKDVKMK PKLIGLFLAV GLIPILLVGV WSGFQATRAL MKASYGQLQA VRGIKKAQIE
     RFFVERQGDM AVLVETVHSL QNAAFAKLSV AQQLKKAHLE EYLTRMQGSL RNLKDDPLVL
     TALIEFETAF ELSGKKVLTP EWNSVLQKYD ARFQDILKDN NWYDLFLIHA NGNIVYTAKK
     EADLGTIIPE SNLKDASLGK TFELARSMTA EEIAVADFDP YAPSGGQQAA FMIAQIRDEY
     RQLKGFVAMQ MPTDQIVAIV QQRDGLGKTG ETYIVGASND KTVLRSPLTT RSDGALSIGT
     EVSASYIQDA LAGKSGQQVS TDESGKLILV DYAPCHIAGL RWACISKMEL EEAIVPQYEN
     GKDFFARYIE KYGYYDLFLI HPDGDVFYSV SHEADYGTNM LKGQYADSNL GKLVKQTVET
     KLFGMADFAP YAPSNNEPAA FIAQPVIAND QIQLIVGLQL SLEAIDRVMQ QREGMGKSGE
     TYLVGADKLM RSDSVLDPEY HSVKASFANP EKGKVETKAV KKALSGESGD AIISDYRGNR
     VLSGYTPVSI FGTTWALLAE IDNSEVKAPV YMLILTIAII GVVLGVAVAL FARSLAASIA
     APLTLGVEFA KSVAAGDLTQ NIEVTQQDEI GMLADALNDM VKKLREIVMD VKGAADNVAY
     GSQQLSSSSE EMSQGATEQA ASAEQASSSM EEMTANIRQN AENAGHTERI AIKSAADAGD
     SGKAVAETVE AMRSISEKIL VIDDIARQTN LLSLNATIEA SKAGEQGRGF AVVAAEIRSL
     AERSRGEAAD INKVARTSVA IAERAGEMLN KLVPDIQRTA ELVQEISAAS REQDSGAGQI
     NQAIQQLDQV IQQNASVSEE LASTAEELSG QAEQLQMTMS FFKVHHLEQH EKKETDGTTS
     QRVIHKVAHI KTQPAAASGN NGSGYEERRV DRIAPHVPVP RDEHDDEFER Y
//