ID A0A0S7BBY0_9CHLR Unreviewed; 750 AA.
AC A0A0S7BBY0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Adenylate cyclase, family 3 {ECO:0000313|EMBL:GAP12272.1};
GN ORFNames=LARV_00003 {ECO:0000313|EMBL:GAP12272.1};
OS Longilinea arvoryzae.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Longilinea.
OX NCBI_TaxID=360412 {ECO:0000313|EMBL:GAP12272.1};
RN [1] {ECO:0000313|EMBL:GAP12272.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KOME-1 {ECO:0000313|EMBL:GAP12272.1};
RA Sekiguchi Y., Ohashi A., Matsuura N., Tourlousse M.D.;
RT "Draft Genome Sequences of Anaerolinea thermolimosa IMO-1, Bellilinea
RT caldifistulae GOMI-1, Leptolinea tardivitalis YMTK-2, Levilinea
RT saccharolytica KIBI-1,Longilinea arvoryzae KOME-1, Previously Described as
RT Members of the Anaerolineaceae (Chloroflexi).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
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DR EMBL; DF967972; GAP12272.1; -; Genomic_DNA.
DR RefSeq; WP_075071715.1; NZ_DF967972.1.
DR AlphaFoldDB; A0A0S7BBY0; -.
DR STRING; 360412.LARV_00003; -.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000055060; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029150; dCache_3.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR Pfam; PF14827; dCache_3; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000055060};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 155..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..118
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 461..513
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 549..684
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 121..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 53
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 750 AA; 81846 MW; A12171DA7598974D CRC64;
MPRKVLILQS EPKNAVALAG LFRARGDEVW LAKDLDQARS MLGQVLPNLV MMDLHFPGKT
WSDFLRDLRR DQPDLNIIMT NTHPDLQREM AVQALGVSVF LRAPFTNQWL DVALRRAEGG
LSPNTRPTAG AQAAKPVKKD QAAPRVRMPV RFKITLPYLL LAVILASAAA LIISQVMLDS
IQDRFLNQLL ETGRQSSDWM VREENRMLST LRLVANTQGV AAAVQSGDAE GLRSLTLPAI
VNAGEETVEF LDMQGVSVLG LRPGTSGQAG EYASVRGETI FQPVGFVQAV LQGRSDEQGD
KFAGVQDTPF GRYFYVSGPI FDPSGDQVGA LLVGKSIHSL ATAMSSDTTS QVTIYDLDGQ
PLSSVLFTDT ESFPLARNQV GNVLIQQDQS TLTRDLTISQ VGYSELLLPW EVRNGADLGV
LGVALEQTFL VRTTQITRLE VFILMVVAIL MVIGVGLFLS SLITKPLLKL VHASSEVARG
NLEVKVDSGG DDEVAVLAQS FNFMVAGLQE GYIYRDLLGR TVSPEVREQL RQTFGSGNLR
LEGQEAVASV LMTDIRGFTT LSEKASPATV FNWLNEYFGR LVPIVVSHGG VVNKFDGDAM
LAFFGILPRM LNPRRSAKDA CDSAVEMLRA INSLNRERVQ RGDPPLLTGI GIHTGVVIAG
GLGTSDRLHY TIIGDTVNTS QRLESLTREL FAETGALISQ PTLLALGDSQ TDYRLEPMGK
HSVKGKTEQL MVYRLNELPN LNPQRPGRPI
//
