ID A0A0S7BS88_9CHLR Unreviewed; 828 AA.
AC A0A0S7BS88;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:GAP40574.1};
GN ORFNames=ATC1_13551 {ECO:0000313|EMBL:GAP40574.1};
OS Flexilinea flocculi.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Flexilinea.
OX NCBI_TaxID=1678840 {ECO:0000313|EMBL:GAP40574.1};
RN [1] {ECO:0000313|EMBL:GAP40574.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC1 {ECO:0000313|EMBL:GAP40574.1};
RA Matsuura N., Tourlousse D.M., Sun L., Toyonaga M., Kuroda K., Ohashi A.,
RA Cruz R., Yamaguchi T., Sekiguchi Y.;
RT "Draft Genome Sequence of Anaerolineae Strain TC1, a Novel Isolate from a
RT Methanogenic Wastewater Treatment System.";
RL Genome Announc. 3:e01104-15(2015).
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
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DR EMBL; DF968181; GAP40574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7BS88; -.
DR STRING; 1678840.ATC1_13551; -.
DR PATRIC; fig|1678840.3.peg.1857; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000053370; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Hydrolase {ECO:0000313|EMBL:GAP40574.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:GAP40574.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053370};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 4..151
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
SQ SEQUENCE 828 AA; 93638 MW; 520B4116769B9710 CRC64;
MMRFDRFTEK AQDAAQRAVE ILQRYGQNQI DTEHFLLALI EQPEGIVSQI LDEMNVSTAT
LADRLDFLLR TTTKANIYGG GSGQIFITPN VRRIVDQAYT EANRLKDEFT STEHLFLAIL
NEKGTAVAKL LEELGITRAK VFEIIVKMRD GKHITEQAGE IKYKTLQKYS VDLTQRAREG
KLDPVIGREA EILRVMQILC RRTKNNPVLI GEAGVGKTAI VEGLAQKIAI NDVPELLSGK
KVISLDMGAM VAGSKFRGEF EERIKIIIEE VQKSNGEIIL FIDELHTVIG AGASQGSIDA
SNMLKPALSR GELQCIGATT LDEYHKYIEK DTALERRFAS VYVEEPSEAV TLKMLQGLKG
KYEQHHKVLY KPEALEAAVR LSSRFVSDRK RPDKAIDLID EAAAKLRVAL FSLPDDLKAM
KTEIDKLAAE EEQAGVERDY EKAAKIKAER LRIQDEFSKK RDAWEQEHHL DEEVDVDDIA
QIVALWTGIP VNQMLENETD RLVHMEERLH ENIIGQHEAI HAVADAIRRS RSGLKDPSRP
IGSFIFIGPS GVGKTELAKA IAKFLFDDED ALVRIDMSEY REQHTVSRLF GAPPGYVGYE
EGGQLTEAIR RRPYRVILFD EIEKAHPEVW NSLLQILDDG RLTDGQGRQV DFRNTVLVMT
SNLGTEYINK AGTLGFIGSE QDNEDRESKL KIDKALKSTF RPEFLNRIDE IIMFSKLSIE
DMEKIVDLQM NEIRQRVNEN GLEIELDPEA KKWLAKIGYD PAFGARPLRR ALQKYIESPI
SIQWLSGTLK KGDHIKIVKK ESAEELDFLR MNEKKAANNT GITQQFEK
//
