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Database: UniProt
Entry: A0A0S7C0W6_9BACT
LinkDB: A0A0S7C0W6_9BACT
Original site: A0A0S7C0W6_9BACT 
ID   A0A0S7C0W6_9BACT        Unreviewed;       478 AA.
AC   A0A0S7C0W6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   25-OCT-2017, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=TBC1_12396 {ECO:0000313|EMBL:GAP44587.1};
OS   Lentimicrobium saccharophilum.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales;
OC   Lentimicrobiaceae; Lentimicrobium.
OX   NCBI_TaxID=1678841 {ECO:0000313|EMBL:GAP44587.1, ECO:0000313|Proteomes:UP000053091};
RN   [1] {ECO:0000313|Proteomes:UP000053091}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TBC1 {ECO:0000313|Proteomes:UP000053091};
RA   Tourlousse D.M., Matsuura N., Sun L., Toyonaga M., Kuroda K.,
RA   Ohashi A., Cruz R., Yamaguchi T., Sekiguchi Y.;
RT   "Draft Genome Sequence of Bacteroidales Strain TBC1, a Novel Isolate
RT   from a Methanogenic Wastewater Treatment System.";
RL   Genome Announc. 3:e01168-15(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; DF968183; GAP44587.1; -; Genomic_DNA.
DR   RefSeq; WP_062044134.1; NZ_DF968183.1.
DR   EnsemblBacteria; GAP44587; GAP44587; TBC1_12396.
DR   PATRIC; fig|1678841.3.peg.3098; -.
DR   Proteomes; UP000053091; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053091};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053091}.
FT   DOMAIN      175    311       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      386    455       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     183    190       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   478 AA;  54959 MW;  E17460388EAE98DD CRC64;
     MRKDYQEVWE NCLRIIKDNI NYQSFKTWFS PIKPVKLDEN VLTIQVPSQF FYEWLEEHYI
     NLLKKTIKQE LGQNGRLEYS IIMESSNDAR PPYTIQVPTS NKGLLANPSV SMPIDLNKGS
     TKEIPNPFVI PGLRKIKVHS QLNESYSFDN FIEGDCNRLA RSAGYAVATN PGKTAFNPIF
     IYSANGLGKT HLAHAIGIQV KNNFPDKTVL YVTAEQFIQQ FIDAVKNSNQ NDFVHFYQMI
     DVLLIDDIQF LSGKEKTQDV FFHIFNHLHQ NGHQLVITSD KAPVEMKGIE PRLLSRFKWG
     LAADLQVPDL ETRIAILNKR LYKDGIDMPE EVIEYLAYSI TTNIRELEGA LISLMAQSSL
     NKKAITIDLA RQMIDKFVKN TSKEISIDYI QKIVCDFFNI HVDHLNSKTR KREIVQARQL
     AMYFSKKHTK SSLATIGLHC GNKDHATVLH ACRTVNNLIE TDKQFRNYVE EIEKKIKI
//
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