ID   A0A0S7DT38_9EURO        Unreviewed;      1463 AA.
AC   A0A0S7DT38;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Vacuolar import and degradation protein 21 {ECO:0000256|ARBA:ARBA00029670};
GN   ORFNames=ALT_008200 {ECO:0000313|EMBL:GIM39717.1};
OS   Aspergillus lentulus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=293939 {ECO:0000313|EMBL:GIM39717.1};
RN   [1] {ECO:0000313|EMBL:GIM39717.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=IFM 54703 {ECO:0000313|EMBL:GIM39717.1};
RA   Kusuya Y., Sakai K., Kamei K., Takahashi H., Yaguchi T.;
RT   "Draft Genome sequence of the pathogenic filamentous fungus Aspergillus
RT   lentulus IFM 54703T.";
RL   Genome Announc. 4:e01568-15(2016).
CC   -!- FUNCTION: Component of the NuA4 histone acetyltransferase complex which
CC       is involved in transcriptional activation of selected genes principally
CC       by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is
CC       also involved in DNA repair. {ECO:0000256|ARBA:ARBA00025178}.
CC   -!- SIMILARITY: Belongs to the EAF1 family.
CC       {ECO:0000256|ARBA:ARBA00008913}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GIM39717.1}.
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DR   EMBL; BCLY01000009; GIM39717.1; -; Genomic_DNA.
DR   STRING; 293939.A0A0S7DT38; -.
DR   VEuPathDB; FungiDB:TMP_alenIFM54703_5347; -.
DR   GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IEA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd00167; SANT; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR014012; HSA_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   PANTHER; PTHR46459:SF1; E1A-BINDING PROTEIN P400; 1.
DR   PANTHER; PTHR46459; E1A-BINDING PROTEIN P400-RELATED; 1.
DR   Pfam; PF07529; HSA; 1.
DR   Pfam; PF13921; Myb_DNA-bind_6; 1.
DR   SMART; SM00573; HSA; 1.
DR   SMART; SM00717; SANT; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS51204; HSA; 1.
DR   PROSITE; PS50090; MYB_LIKE; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204}.
SQ   SEQUENCE   1463 AA;  160925 MW;  96E1D53714AC5BFF CRC64;
     MLRDELLRSK NDEIARCLLS RKRKLSELYF ATVGFAGATE IAPTNALYHQ REQTFLDAND
     LSKGRYFNEA TLPPFPDFAA LIPRPEEQQT SPEVIEPVVQ TQDVSVNAPK AEGAVRGIAP
     SFQQREGQTA QVIERRLVED SLKKDDARIH QQPALAATSE IPQVAKSPAT SAQPDQLPQK
     ASFAVPETPP TSTSHESADV SVSPALKEQP PGEVVPPRAA SNQLPSAQRK PESRPSLALA
     QSLEDQPLSP ASSAGPYSNN TPAPVAVSPD TSPAEEVTEA ADEVALSPKH VGPVQLQPGL
     VPSTPDEQLQ LEAAQSLQQN TLAGKSISDV TTASSLSNEV IKEDVGSPPS AAADPLKETQ
     DQTSASVVPP EPKRPDGVVV TPEESQPLAQ RIQEGTQPQV GAELKAVAPM TPAGKKPTAA
     AMVPAQPERM TTRVSSGAIR HKSVSEILGE TPKPSVVQPE KAHPIEKPAD MVRARPSASP
     ESAAKMRLKD RKAREKERSK LSTVVFPKQQ QQQQQQQEKD DSLDIVRQYA GELARLNEEQ
     DYLFTLFQNK AYAPPRGTNL STLLASAHKT LTTSNHLLEY QEQMDCRTLR RIYALQNANR
     WPLRQLKRSV EPPRQGTHWD VLLDHMKWMR TDFREERKWK LAAAKSCADW CAEYVNSDPE
     HRALLRVPCR IPSSNLEKKE VHASSMISPP EETTEEMLVV SQPTPDLIPS AEDESVSDGF
     NDEIRHDIRD TVAPAAIFSL GSDEFTFSLD MTPAAQKLLD ELPIYTPVKV APGTNLPMFE
     QPPDSAWKTE LLPVSKYASG RIKFHETEPP RKRSRYDYSQ YDSNPEHGML DLPPEQTNVA
     LFRPENKPIR DRIHPGHSFR PPTEYPMPSV GFFESRQSSQ WTYAEDDELR RLVKEYSYNW
     SLISSCLTPS SQFTSGAERR TPWECFERWV GLEGLPADMS KTQYFRAYHQ RIETAQRTVL
     AQQQAAQQQQ QQQQQGGNNS GQAQPPIRRR TTQPVRVDRR RSSKHLALLD AMRKLAKKRE
     TMLQKQQHAS HLASLRKVNE ANQPKPPISS PAEFSRLKYD RELKLQERQE QYRQQMIAQQ
     RANLAAQRAG QIPNQQPMMN APPGRTPNGI PHNPGTPGIP GATPNGMPNG MPNALPNGIP
     SGMGVSQGRP HMQGMPTGGP PMNGPIPPNP MAMKMMPQAG MPQGPGGRPG MPMQTSPDNT
     RVMREANRLQ EQQRIVQSRQ QQPQPPQHQQ PQAQQAQQQF HNQQQFGPQG SHSPNMNLPH
     VNGAPNNPAM MAALQAGSGM QSPSLHNAMP QGMSTPSPRM GQPNLLSGGV VPTISSIQTQ
     IQRSNPNMPP EQVNKLATDR LHQYQQQRMS QVAMNAAAGN MASVQANYQV PHDANFQSPQ
     PGMNGGPGMQ VPQSQGFSPM MRVPQPAQQN RMGVGNSPAM NGTLAQQSRS ATPQTQRSGS
     AQAGPVPGSS KSPHPPQAQI PSG
//