ID A0A0S7E5F4_9EURO Unreviewed; 1216 AA.
AC A0A0S7E5F4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Intermediate filament protein {ECO:0000313|EMBL:GIM43006.1};
GN ORFNames=ALT_002620 {ECO:0000313|EMBL:GIM43006.1};
OS Aspergillus lentulus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=293939 {ECO:0000313|EMBL:GIM43006.1};
RN [1] {ECO:0000313|EMBL:GIM43006.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFM 54703 {ECO:0000313|EMBL:GIM43006.1};
RA Kusuya Y., Sakai K., Kamei K., Takahashi H., Yaguchi T.;
RT "Draft Genome sequence of the pathogenic filamentous fungus Aspergillus
RT lentulus IFM 54703T.";
RL Genome Announc. 4:e01568-15(2016).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GIM43006.1}.
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DR EMBL; BCLY01000016; GIM43006.1; -; Genomic_DNA.
DR STRING; 293939.A0A0S7E5F4; -.
DR VEuPathDB; FungiDB:TMP_alenIFM54703_8532; -.
DR OrthoDB; 5392990at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06876; PX_MDM1p; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 564..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1216 AA; 136029 MW; 462F1C9E18107783 CRC64;
MALNRRDIIL FSTGGFIAWG LVVRWLPILR YLGYALVLGA LLSCTALLTA VFLTIRPLDS
AKPPRPSSLP LAFLLPKHWP REVEGIRARS TYRADSLYPQ SFIVSESIDE LLSLVTRDFI
ASWYQHISPN PAFVNEVDRV IRAAIGNLCN RLLAEDLISL VVSRIFPILT AHLKEFDVAE
KSVRGRNLTR NVTESEELDL AIAKKYRDGR LHPAAALSVS EQKVVEQEYL RKITLGLLPK
LFPEHVLNSR IVTVLIREIL ACAVLFPLVS VLSDPDTWNQ LVEAYGRTTI QDRKTVQKIR
AALDEHASPA PKTKRGHPFP KLAPNDSERA FERFVRAIRR CNNLSDARRF RALVASQLKR
ESMVEGQDPV YLRRLETGKR VLDQKVAKLS APGGNNTPYA NAVESHFRRN SSSSKPEASL
VDVMHDASGL SYFMEFMDRQ KLMSLVQFWI VVDGFRNPLE DDFGDETSPS SSTWTTADRN
DMALISETYL AKPELKVSEE ARRAVKAFLN AGKRATPEQY RKARTVILST QSAVLEELQA
VYYPKFKQSD LYYKYLASDE VSVAGSRASP APVESPARRP LPPLMARTAS HPGQKPKDLR
RAVASSSDVR SMGKLFDDEE ETRRSIDSER SAPLFDDDYD TDPLAASTHS LGTDSQSGFN
DATQKQAIKS MEAALNDIIT NDPGNANLGD VKYIDSGSAG SFSVDRGLKS PRSTGDLGRL
DNRTDDNKAK PNIASLGLVD QSSRIGVFDD ELFPDQQKFL EDEYDEPPET DDKDPADEVQ
EAAPGDLGLT EAIEALTADI EKLAAQEAVI DALTRKADLT NNTAELRILR KSKASIQREI
HRKEMQRQQY IIQESDNSLY GRSTVRIQSI VVGKEEDGRE YAMYVIEVQR NAGEQMPAAS
WAVARRYSEF HELHQRLRMS YPSVRHLEFP RRRMVMKLQK EFLQKRRLAL EAYLRNLLLL
PEVCRSRDLR AFLSQRAIIP RDETPRDGET KDLVTRIYNS VADGMDDFLG NFGVLDQLSA
AGQNLISAAT NHQNSLVSNS GLATEDAVTA AEAEAELNAF EDRELEPFIK PICDLFLEAF
ELNKGNNWLR GRAVVVVLHQ LLGGTIERKV REGARSLVQD ESLLRYLSMA KETMWPGGVL
RQNKVRTASE RLKSRTEASL VLATLIPDVA GNVVGRANAQ GAARRIFATL NNQRLNSHLI
FSILDEVVLV LFGGAK
//
