ID A0A0S7WX15_9BACT Unreviewed; 637 AA.
AC A0A0S7WX15;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504, ECO:0000256|RuleBase:RU003587};
GN ORFNames=AMJ47_03715 {ECO:0000313|EMBL:KPJ54712.1};
OS Parcubacteria bacterium DG_72.
OC Bacteria; Candidatus Parcubacteria.
OX NCBI_TaxID=1703764 {ECO:0000313|EMBL:KPJ54712.1, ECO:0000313|Proteomes:UP000051392};
RN [1] {ECO:0000313|EMBL:KPJ54712.1, ECO:0000313|Proteomes:UP000051392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_72 {ECO:0000313|EMBL:KPJ54712.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033, ECO:0000256|RuleBase:RU003587}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- SIMILARITY: Belongs to the UvrB family. {ECO:0000256|ARBA:ARBA00008533,
CC ECO:0000256|RuleBase:RU003587}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ54712.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJND01000007; KPJ54712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7WX15; -.
DR STRING; 1703764.AMJ47_03715; -.
DR PATRIC; fig|1703764.3.peg.805; -.
DR Proteomes; UP000051392; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd17916; DEXHc_UvrB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR NCBIfam; TIGR00631; uvrb; 1.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003587};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769,
KW ECO:0000256|RuleBase:RU003587};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003587};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881,
KW ECO:0000256|RuleBase:RU003587};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW SOS response {ECO:0000256|RuleBase:RU003587}.
FT DOMAIN 24..235
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 424..586
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 611..637
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 247..281
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 637 AA; 74183 MW; 45BA7330245CE9B3 CRC64;
MPFKLISKLK PAGEQPKAIK ELVKNIKNGQ KHQVLLGVTG SGKTYVMSNI VKQTQMPGLV
ISHNKTLAAQ LYQEFKDFFP NNAVHYFVSY YDYYQPEAYI PQTDTYIEKD AKINQEIDRL
RHAAVQDLIS RKDIIITASV SCIYNIGSPE DYESVSLKIT NGQEIKRKDF LARLTALQYK
RNDTSFEPGQ FRVRGDNIGI HLVTGEEILQ IEFSGDKINK IVQNKKEHQK VQIFPASFWI
SPEEKLKIAI ENIKLELQER LKQLKSQNKL LETQRLEQRT NYDLEMLAET GYCHGIENYS
SHMEFRKPGD PPFSLIDYFK KFHKNFLIFV DESHQTLPQV KAMAVQDRIR KQTLIDNGFR
LPSAIDNRPL TFKEFEKRIN KVIYVSATPS LYEKNKANKN IVELLIRPTG LLEPKIELKP
TKNQLEDLIK EINKRIEKKQ KVLVLTLTKR LAEAISDYLA EKKIKNKWLH SEVKTLERPE
ILRNLRMGKY DVLVGINLLR EGLDLPEVSL VAILDADKEG FLRNETTLIQ IMGRAARHSE
GSIILYAEKE TESIKKAIKE INRRRKIQQD YNKKHNIIPK AINKEIRDWE FLQKEKQIAS
EFMMIKDKKF LEKEMKKAAK ELDFERAAEI RDLIKKL
//
